ID A0A1X3K4Y8_ECOLX Unreviewed; 709 AA. AC A0A1X3K4Y8; DT 05-JUL-2017, integrated into UniProtKB/TrEMBL. DT 05-JUL-2017, sequence version 1. DT 07-OCT-2020, entry version 6. DE SubName: Full=Replication protein A protein (GpA) {ECO:0000313|EMBL:OSL42261.1}; GN ORFNames=EARG_01344 {ECO:0000313|EMBL:OSL42261.1}; OS Escherichia coli H461. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=656403 {ECO:0000313|EMBL:OSL42261.1, ECO:0000313|Proteomes:UP000193714}; RN [1] {ECO:0000313|EMBL:OSL42261.1, ECO:0000313|Proteomes:UP000193714} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H461 {ECO:0000313|EMBL:OSL42261.1, RC ECO:0000313|Proteomes:UP000193714}; RG The Broad Institute Genome Sequencing Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q., RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D., RA Larson L., Mehta T., Park D., Pearson M., Richards J., Roberts A., Saif S., RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.; RT "The Genome Sequence of Escherichia coli H461."; RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Possible endonuclease which induces a single-strand cut and CC initiates DNA replication. {ECO:0000256|ARBA:ARBA00003293}. CC -!- SIMILARITY: Belongs to the phage GPA family. CC {ECO:0000256|ARBA:ARBA00009260}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OSL42261.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ADJV01000021; OSL42261.1; -; Genomic_DNA. DR Proteomes; UP000193714; Unassembled WGS sequence. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR008766; Replication_gene_A. DR Pfam; PF05840; Phage_GPA; 1. PE 3: Inferred from homology; KW DNA replication {ECO:0000256|ARBA:ARBA00022705}; KW Endonuclease {ECO:0000256|ARBA:ARBA00022759}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Nuclease {ECO:0000256|ARBA:ARBA00022722}. SQ SEQUENCE 709 AA; 79953 MW; 17B6929BB921ED2F CRC64; MFAALLHAKK VLSLQPDCVR LDVYRTAAVL EQNQGSQRAN AFLISFCKKA LPRLELVAKK YECAGINSKV STAVFGSHFD TQQMQYLSSR MVNMVARYNR LPDMSRADVD LLAADIANFI RGELANINDH GFGELKTLYT WYIRAGFISL QFNVIPPHWE RVEKKYVGAD EIAPAIAKMF NDGWWRGRLR RVAATWREHL QIAVGNVSKK KNTYASKNCV TDWREQKRRT REFLKGLDLE DEDGNRISLI EKYDGSVANP AIRRCELMTR IRGFENICNE LGYVGEFYTL TAPSKYHATT KAGYRNSKWS GASPADTQNY LTGIWARIRA KLHREDVRIF GIRVAEPHHD GTPHWHMLMF MLPEDVEYVR SIVRKYAWKE DRHELKSDKS QKARFHAESI DPEKGSATGY VAKYISKNID GYALDGETDD ESGELLKETA PAVSAWAARW HIRQFQFIGG APVTVYRELR RLADTETAHG LSVEFAAVHD AADAGDWAGY VNAQGGPFVR RDDLQVRTLY EPRTELNQYG EETVCIKGVY DSSIGAGSPI LTRLTQWKIV PKRAVDLAVD LQDGKAVPRS SVNNCTGSES DPPILDLTKP LSRRERRELT NRLRKQKPAA RRKFIHGTDE QNAAIAKTID EIHLTTGINI SRGEALHLMA GGKSCFDGKW LRGTAKGEIF SAAPSHEAKA RKILNRVAAM AEASKPIHE //