ID A0A1X0P6D4_9TRYP Unreviewed; 262 AA. AC A0A1X0P6D4; DT 05-JUL-2017, integrated into UniProtKB/TrEMBL. DT 05-JUL-2017, sequence version 1. DT 03-AUG-2022, entry version 18. DE SubName: Full=Synaptobrevin-type transport protein {ECO:0000313|EMBL:ORC92492.1}; GN ORFNames=TM35_000032450 {ECO:0000313|EMBL:ORC92492.1}; OS Trypanosoma theileri. OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; OC Trypanosomatida; Trypanosomatidae; Trypanosoma. OX NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC92492.1, ECO:0000313|Proteomes:UP000192257}; RN [1] {ECO:0000313|EMBL:ORC92492.1, ECO:0000313|Proteomes:UP000192257} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Edinburgh {ECO:0000313|EMBL:ORC92492.1}; RA Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P., RA Matthews J., Matthews K., Carrington M.; RT "An alternative strategy for trypanosome survival in the mammalian RT bloodstream revealed through genome and transcriptome analysis of the RT ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri."; RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein CC {ECO:0000256|ARBA:ARBA00004163}. Membrane CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein CC {ECO:0000256|ARBA:ARBA00004211}. CC -!- SIMILARITY: Belongs to the synaptobrevin family. CC {ECO:0000256|ARBA:ARBA00008025}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:ORC92492.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; NBCO01000003; ORC92492.1; -; Genomic_DNA. DR STRING; 67003.A0A1X0P6D4; -. DR VEuPathDB; TriTrypDB:TM35_000032450; -. DR OrthoDB; 903466at2759; -. DR Proteomes; UP000192257; Unassembled WGS sequence. DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro. DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro. DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro. DR CDD; cd14824; Longin; 1. DR InterPro; IPR011012; Longin-like_dom_sf. DR InterPro; IPR010908; Longin_dom. DR InterPro; IPR044565; Sec22. DR InterPro; IPR042855; V_SNARE_CC. DR PANTHER; PTHR45837; PTHR45837; 1. DR Pfam; PF00957; Synaptobrevin; 1. DR SUPFAM; SSF64356; SSF64356; 1. DR PROSITE; PS50892; V_SNARE; 1. PE 3: Inferred from homology; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE- KW ProRule:PRU00290}; Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000192257}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 239..261 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 181..241 FT /note="V-SNARE coiled-coil homology" FT /evidence="ECO:0000259|PROSITE:PS50892" SQ SEQUENCE 262 AA; 30153 MW; 9800EDC0650B294D CRC64; MASKGCFIAV LIARTHDHVP LCSYTDENYA NCNQIRQQEQ RILERMESPA ATADRKDAKG CYYQSFDHRD CIYFAFQDAA TDLTIITAVN KLLLRNSGDI AATNRLACGL LDLVFAEFMR MYSVTEIVAK TVRPFQFIKF DTTLQKLILQ VQQDKRGDNV LIGGTGAAQQ GTGQRRQVNP HYDALRQELT DVHFVMRKNL EDLMTRGEKL ETMNQFSAQL VDQSSRFYKK TVHMNRMRLL RLYGPPAVVG IILIIFFYFY FF //