ID A0A1W7QSI8_9DELT Unreviewed; 449 AA. AC A0A1W7QSI8; DT 05-JUL-2017, integrated into UniProtKB/TrEMBL. DT 05-JUL-2017, sequence version 1. DT 29-SEP-2021, entry version 9. DE RecName: Full=Replicative DNA helicase {ECO:0000256|ARBA:ARBA00021957, ECO:0000256|RuleBase:RU362085}; DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU362085}; GN ORFNames=GPEL0_01f2444 {ECO:0000313|EMBL:GAW66891.1}; OS Geobacter pelophilus. OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales; OC Geobacteraceae; Geobacter. OX NCBI_TaxID=60036 {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153}; RN [1] {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Drf2 {ECO:0000313|EMBL:GAW66891.1, RC ECO:0000313|Proteomes:UP000194153}; RG Geobacter pelophilus Genome Sequencing; RA Aoyagi T., Koike H., Hori T.; RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Drf2 {ECO:0000313|EMBL:GAW66891.1, RC ECO:0000313|Proteomes:UP000194153}; RA Aoyagi T., Koike H., Morita T., Sato Y., Habe H., Hori T.; RT "Draft genome sequence of Geobacter pelophilus, a iron(III)-reducing RT bacteria."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Participates in initiation and elongation during chromosome CC replication; it exhibits DNA-dependent ATPase activity and contains CC distinct active sites for ATP binding, DNA binding, and interaction CC with DnaC protein, primase, and other prepriming proteins. CC {ECO:0000256|ARBA:ARBA00003574, ECO:0000256|RuleBase:RU362085}. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12; CC Evidence={ECO:0000256|ARBA:ARBA00001665, CC ECO:0000256|RuleBase:RU362085}; CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily. CC {ECO:0000256|ARBA:ARBA00008428, ECO:0000256|RuleBase:RU362085}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:GAW66891.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BDQG01000001; GAW66891.1; -; Genomic_DNA. DR Proteomes; UP000194153; Unassembled WGS sequence. DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0140603; F:ATP hydrolysis activity; IEA:RHEA. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule. DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule. DR CDD; cd00984; DnaB_C; 1. DR Gene3D; 1.10.860.10; -; 1. DR Gene3D; 3.40.50.300; -; 1. DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf. DR InterPro; IPR007692; DNA_helicase_DnaB. DR InterPro; IPR007694; DNA_helicase_DnaB-like_C. DR InterPro; IPR007693; DNA_helicase_DnaB-like_N. DR InterPro; IPR016136; DNA_helicase_N/primase_C. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00772; DnaB; 1. DR Pfam; PF03796; DnaB_C; 1. DR SUPFAM; SSF48024; SSF48024; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00665; DnaB; 1. DR PROSITE; PS51199; SF4_HELICASE; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362085}; KW DNA replication {ECO:0000256|ARBA:ARBA00022705, KW ECO:0000256|RuleBase:RU362085}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362085}; KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU362085}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362085}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, KW ECO:0000256|RuleBase:RU362085}; KW Primosome {ECO:0000256|ARBA:ARBA00022515, ECO:0000256|RuleBase:RU362085}. FT DOMAIN 179..447 FT /note="SF4 helicase" FT /evidence="ECO:0000259|PROSITE:PS51199" SQ SEQUENCE 449 AA; 50356 MW; 5A246901041706C9 CRC64; MNATDMRKLP PQSIEAEMSI LGGILVDNEA INRVLEILVP DDLYRESHRK ILRAMIELNE RGEPCDLITM TTILRKKGEL EEVGGGAYLA TLVDFVPMAA NISYYCKIVK EKWLTRKLIS AATDIVSKGF EDKVDTEELL DAAQKVIFEI SENKIRPAYY QVSDILKDTI KNIELLYEKK ELVTGVPTGY TDLDKLTAGF HAGDLVIIAG RPAMGKTTFA LNVAQYAAID ADQAYPAAVF SLEMPKEQLV ERLLCSVAKV DLSRLRSGHL VENDWPKLIK AGGKLHDAKI FIDDTPSITI MELRSKARRL KAEHNIGLIV IDYLQLMRGG ANPESRQQEI SEISRSLKGL AKELSIPVIA LSQLNRGLEQ RSDKRPMMSD LRESGAIEQD ADIIMFVYRE EVYEKDKEDL KGKAEVIIGK HRSGPTGTVH LAFRGEFTRF ENLSSRDDY //