ID A0A1W7QSI8_9DELT Unreviewed; 449 AA. AC A0A1W7QSI8; DT 05-JUL-2017, integrated into UniProtKB/TrEMBL. DT 05-JUL-2017, sequence version 1. DT 05-DEC-2018, entry version 5. DE RecName: Full=Replicative DNA helicase {ECO:0000256|RuleBase:RU362085}; DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU362085}; GN ORFNames=GPEL0_01f2444 {ECO:0000313|EMBL:GAW66891.1}; OS Geobacter pelophilus. OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales; OC Geobacteraceae; Geobacter. OX NCBI_TaxID=60036 {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153}; RN [1] {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Drf2 {ECO:0000313|EMBL:GAW66891.1, RC ECO:0000313|Proteomes:UP000194153}; RG Geobacter pelophilus Genome Sequencing; RA Aoyagi T., Koike H., Hori T.; RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:GAW66891.1, ECO:0000313|Proteomes:UP000194153} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Drf2 {ECO:0000313|EMBL:GAW66891.1, RC ECO:0000313|Proteomes:UP000194153}; RA Aoyagi T., Koike H., Morita T., Sato Y., Habe H., Hori T.; RT "Draft genome sequence of Geobacter pelophilus, a iron(III)-reducing RT bacteria."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Participates in initiation and elongation during CC chromosome replication; it exhibits DNA-dependent ATPase activity CC and contains distinct active sites for ATP binding, DNA binding, CC and interaction with DnaC protein, primase, and other prepriming CC proteins. {ECO:0000256|RuleBase:RU362085}. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12; CC Evidence={ECO:0000256|RuleBase:RU362085}; CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily. CC {ECO:0000256|RuleBase:RU362085}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:GAW66891.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BDQG01000001; GAW66891.1; -; Genomic_DNA. DR Proteomes; UP000194153; Unassembled WGS sequence. DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule. DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule. DR CDD; cd00984; DnaB_C; 1. DR Gene3D; 1.10.860.10; -; 1. DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf. DR InterPro; IPR007692; DNA_helicase_DnaB. DR InterPro; IPR007694; DNA_helicase_DnaB-like_C. DR InterPro; IPR007693; DNA_helicase_DnaB-like_N. DR InterPro; IPR016136; DNA_helicase_N/primase_C. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00772; DnaB; 1. DR Pfam; PF03796; DnaB_C; 1. DR SUPFAM; SSF48024; SSF48024; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00665; DnaB; 1. DR PROSITE; PS51199; SF4_HELICASE; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|RuleBase:RU362085}; KW Complete proteome {ECO:0000313|Proteomes:UP000194153}; KW DNA replication {ECO:0000256|RuleBase:RU362085, KW ECO:0000256|SAAS:SAAS00740714}; KW DNA-binding {ECO:0000256|RuleBase:RU362085, KW ECO:0000256|SAAS:SAAS00740674}; KW Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:GAW66891.1}; KW Hydrolase {ECO:0000256|RuleBase:RU362085}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU362085}; KW Primosome {ECO:0000256|RuleBase:RU362085}. FT DOMAIN 179 447 SF4 helicase. {ECO:0000259|PROSITE: FT PS51199}. SQ SEQUENCE 449 AA; 50356 MW; 5A246901041706C9 CRC64; MNATDMRKLP PQSIEAEMSI LGGILVDNEA INRVLEILVP DDLYRESHRK ILRAMIELNE RGEPCDLITM TTILRKKGEL EEVGGGAYLA TLVDFVPMAA NISYYCKIVK EKWLTRKLIS AATDIVSKGF EDKVDTEELL DAAQKVIFEI SENKIRPAYY QVSDILKDTI KNIELLYEKK ELVTGVPTGY TDLDKLTAGF HAGDLVIIAG RPAMGKTTFA LNVAQYAAID ADQAYPAAVF SLEMPKEQLV ERLLCSVAKV DLSRLRSGHL VENDWPKLIK AGGKLHDAKI FIDDTPSITI MELRSKARRL KAEHNIGLIV IDYLQLMRGG ANPESRQQEI SEISRSLKGL AKELSIPVIA LSQLNRGLEQ RSDKRPMMSD LRESGAIEQD ADIIMFVYRE EVYEKDKEDL KGKAEVIIGK HRSGPTGTVH LAFRGEFTRF ENLSSRDDY //