ID A0A1W2P804_MOUSE Unreviewed; 414 AA. AC A0A1W2P804; DT 07-JUN-2017, integrated into UniProtKB/TrEMBL. DT 05-JUN-2019, sequence version 2. DT 03-MAY-2023, entry version 32. DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551}; DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551}; GN Name=Mcm9 {ECO:0000313|Ensembl:ENSMUSP00000151893.3, GN ECO:0000313|MGI:MGI:1918817}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000151893.3, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000151893.3, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000151893.3, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000151893.3} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000151893.3}; RG Ensembl; RL Submitted (JAN-2023) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}. CC Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A1W2P804; -. DR SMR; A0A1W2P804; -. DR ProteomicsDB; 361642; -. DR Antibodypedia; 34788; 94 antibodies from 24 providers. DR Ensembl; ENSMUST00000218549.3; ENSMUSP00000151893.3; ENSMUSG00000058298.11. DR AGR; MGI:1918817; -. DR MGI; MGI:1918817; Mcm9. DR VEuPathDB; HostDB:ENSMUSG00000058298; -. DR GeneTree; ENSGT01050000244824; -. DR ChiTaRS; Mcm9; mouse. DR Proteomes; UP000000589; Chromosome 10. DR Bgee; ENSMUSG00000058298; Expressed in animal zygote and 161 other tissues. DR ExpressionAtlas; A0A1W2P804; baseline and differential. DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro. DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1. DR InterPro; IPR031327; MCM. DR InterPro; IPR001208; MCM_dom. DR InterPro; IPR033762; MCM_OB. DR InterPro; IPR012340; NA-bd_OB-fold. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR11630:SF48; DNA HELICASE MCM9; 1. DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1. DR Pfam; PF00493; MCM; 1. DR Pfam; PF17207; MCM_OB; 1. DR SMART; SM00350; MCM; 1. DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR PROSITE; PS50051; MCM_2; 1. PE 1: Evidence at protein level; KW Chromosome {ECO:0000256|ARBA:ARBA00022454}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Proteomics identification {ECO:0007829|EPD:A0A1W2P804, KW ECO:0007829|ProteomicsDB:A0A1W2P804}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 323..404 FT /note="MCM" FT /evidence="ECO:0000259|PROSITE:PS50051" SQ SEQUENCE 414 AA; 46421 MW; 628637E17E2D9BA5 CRC64; MNSEQVTLVG QVFESYVSEY HKNDILLILK ERDEDAHYPV VVNAMSLFET NMEIGDYFTV FPNEVLTVFD SALRRSALAI LQSLPETEGL SMKQNLHARI SGLPVCPELV REHIPKTKDV GHFLSVTGTV IRTSLVKVLE FERDYMCNKC KHVFMVEADF EQYYTFSRPS SCPSLASCDS SKFSCLSDLS SSPARCRDYQ EIKIQEQVQR LSVGSIPRSM KVILEDDLVD SCKSVLQCHL TVHDLPAGLT WVLSLGDDLT IYGVVMQRWK PFQRDVRCEV EIVLKANYVQ VNNEQSSGMV MDEDTRKEFE DFWEHYKSDP FAGRNEILAS LCPQVFGMYL VKLAVAMVLA GGIQRTDAAG TRVRGESHLL LVGDPGTGKS QFLKYAAKIT PRSVLTTGIG STSADCFEKC SIKA //