ID   A0A1W2KEI3_9TELE        Unreviewed;       194 AA.
AC   A0A1W2KEI3;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   02-DEC-2020, entry version 15.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
DE            EC=7.1.1.9 {ECO:0000256|RuleBase:RU000369};
DE   Flags: Fragment;
GN   Name=COI {ECO:0000313|EMBL:ANP23606.1};
OS   Sillago asiatica (Asian whiting).
OG   Mitochondrion {ECO:0000313|EMBL:ANP23606.1}.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Sillaginidae; Sillago.
OX   NCBI_TaxID=1055099 {ECO:0000313|EMBL:ANP23606.1};
RN   [1] {ECO:0000313|EMBL:ANP23606.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DYBYZ2 {ECO:0000313|EMBL:ANP23601.1}, DYBYZ4
RC   {ECO:0000313|EMBL:ANP23602.1}, DYCYZ1 {ECO:0000313|EMBL:ANP23603.1},
RC   DYCYZ3 {ECO:0000313|EMBL:ANP23604.1}, DYCYZ5
RC   {ECO:0000313|EMBL:ANP23605.1}, PJYZ14 {ECO:0000313|EMBL:ANP23615.1},
RC   PJYZ17 {ECO:0000313|EMBL:ANP23616.1}, PJYZ22
RC   {ECO:0000313|EMBL:ANP23617.1}, PJYZ5 {ECO:0000313|EMBL:ANP23613.1},
RC   PJYZ8 {ECO:0000313|EMBL:ANP23614.1}, STYZ1
RC   {ECO:0000313|EMBL:ANP23611.1}, SYYZ1 {ECO:0000313|EMBL:ANP23606.1},
RC   SYYZ2 {ECO:0000313|EMBL:ANP23607.1}, SYYZ3
RC   {ECO:0000313|EMBL:ANP23608.1}, SYYZ4 {ECO:0000313|EMBL:ANP23609.1},
RC   and SYYZ5 {ECO:0000313|EMBL:ANP23610.1};
RA   Xiao J., Song N., Han Z., Shao K.-T., McKay R.J., Gao T.;
RT   "Cryptic diversity in Sillaginidae (Perciforms) across the Indo-West
RT   Pacific revealed by DNA barcoding.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ANP23606.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=STYZ1 {ECO:0000313|EMBL:ANP23611.1}, SYYZ1
RC   {ECO:0000313|EMBL:ANP23606.1}, and SYYZ4
RC   {ECO:0000313|EMBL:ANP23609.1};
RA   Xiao J.-G., Song N., Han Z.-Q., Gao T.-X.;
RT   "Description and DNA Barcoding of a New Sillago Species, Sillago shaoi
RT   (Perciformes: Sillaginidae), in the Taiwan Strait.";
RL   Zool. Stud. 55:47-47(2016).
RN   [3] {ECO:0000313|EMBL:AUW64531.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Z4 {ECO:0000313|EMBL:AUW64531.1};
RA   Xiao J., Song N., Gao T.;
RT   "Molecular phylogeny of Sillaginidae (Perciforms): evidence for necessary
RT   taxonomic revision in the family and the identification of cryptic
RT   diversity across the Indo-West Pacific.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the cytochrome c oxidase, the last enzyme in the
CC       mitochondrial electron transport chain which drives oxidative
CC       phosphorylation. The respiratory chain contains 3 multisubunit
CC       complexes succinate dehydrogenase (complex II, CII), ubiquinol-
CC       cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III,
CC       CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to
CC       transfer electrons derived from NADH and succinate to molecular oxygen,
CC       creating an electrochemical gradient over the inner membrane that
CC       drives transmembrane transport and the ATP synthase. Cytochrome c
CC       oxidase is the component of the respiratory chain that catalyzes the
CC       reduction of oxygen to water. Electrons originating from reduced
CC       cytochrome c in the intermembrane space (IMS) are transferred via the
CC       dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1
CC       to the active site in subunit 1, a binuclear center (BNC) formed by
CC       heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2
CC       water molecules using 4 electrons from cytochrome c in the IMS and 4
CC       protons from the mitochondrial matrix. {ECO:0000256|RuleBase:RU000369}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4 [Fe(II)cytochrome c] + 4 H(+) + O2 = 4 [Fe(III)cytochrome c]
CC         + 2 H2O; Xref=Rhea:RHEA:11436, Rhea:RHEA-COMP:10350, Rhea:RHEA-
CC         COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=7.1.1.9;
CC         Evidence={ECO:0000256|RuleBase:RU000369};
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|ARBA:ARBA00001935};
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|ARBA:ARBA00004673, ECO:0000256|RuleBase:RU000369}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU000369}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004448,
CC       ECO:0000256|RuleBase:RU000369}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|ARBA:ARBA00009578, ECO:0000256|RuleBase:RU000369}.
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DR   EMBL; KU051907; ANP23601.1; -; Genomic_DNA.
DR   EMBL; KU051908; ANP23602.1; -; Genomic_DNA.
DR   EMBL; KU051909; ANP23603.1; -; Genomic_DNA.
DR   EMBL; KU051910; ANP23604.1; -; Genomic_DNA.
DR   EMBL; KU051911; ANP23605.1; -; Genomic_DNA.
DR   EMBL; KU051912; ANP23606.1; -; Genomic_DNA.
DR   EMBL; KU051913; ANP23607.1; -; Genomic_DNA.
DR   EMBL; KU051914; ANP23608.1; -; Genomic_DNA.
DR   EMBL; KU051915; ANP23609.1; -; Genomic_DNA.
DR   EMBL; KU051916; ANP23610.1; -; Genomic_DNA.
DR   EMBL; KU051917; ANP23611.1; -; Genomic_DNA.
DR   EMBL; KU051919; ANP23613.1; -; Genomic_DNA.
DR   EMBL; KU051920; ANP23614.1; -; Genomic_DNA.
DR   EMBL; KU051921; ANP23615.1; -; Genomic_DNA.
DR   EMBL; KU051922; ANP23616.1; -; Genomic_DNA.
DR   EMBL; KU051923; ANP23617.1; -; Genomic_DNA.
DR   EMBL; MF571926; AUW64531.1; -; Genomic_DNA.
DR   UniPathway; UPA00705; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR   InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
DR   InterPro; IPR000883; Cyt_C_Oxase_1.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   PROSITE; PS50855; COX1; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|ARBA:ARBA00023008, ECO:0000256|RuleBase:RU000369};
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982,
KW   ECO:0000256|RuleBase:RU000369}; Heme {ECO:0000256|RuleBase:RU000369};
KW   Iron {ECO:0000256|RuleBase:RU000369};
KW   Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000369};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU000369, ECO:0000313|EMBL:ANP23606.1};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW   ECO:0000256|RuleBase:RU000369};
KW   Respiratory chain {ECO:0000256|ARBA:ARBA00022660,
KW   ECO:0000256|RuleBase:RU000369}; Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Translocase {ECO:0000256|ARBA:ARBA00022967};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000369}.
FT   TRANSMEM        34..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..194
FT                   /note="COX1"
FT                   /evidence="ECO:0000259|PROSITE:PS50855"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ANP23606.1"
FT   NON_TER         194
FT                   /evidence="ECO:0000313|EMBL:ANP23606.1"
SQ   SEQUENCE   194 AA;  20582 MW;  DE436B04A5264C15 CRC64;
     WAGMVGTALS LLIRAELSQP GALLGDDQIY NVIVTAHAFV MIFFMVMPIL IGGFGNWLVP
     LMIGAPDMAF PRMNNMSFWL LPPSFLLLLA SSGVEAGAGT GWTVYPPLAG NLAHAGASVD
     LTIFSLHLAG VSSILGAINF ITTIINMKPP ATSQYQTPLF VWSVLITAVL LLLSLPVLAA
     GITMLLTDRN LNTT
//