ID   A0A1W1B5K6_HUMAN        Unreviewed;       138 AA.
AC   A0A1W1B5K6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   22-FEB-2023, entry version 10.
DE   SubName: Full=MHC class II antigen {ECO:0000313|EMBL:SBL08075.1};
DE   Flags: Fragment;
GN   Name=HLA-DQB1 {ECO:0000313|EMBL:SBL08075.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:SBL08075.1};
RN   [1] {ECO:0000313|EMBL:SBL08075.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SBL08075.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Marsh S.G.E.;
RT   "Full-length genomic HLA sequences.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT575499; SBL08075.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W1B5K6; -.
DR   PeptideAtlas; A0A1W1B5K6; -.
DR   ChiTaRS; HLA-DQB1; human.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05766; IgC_MHC_II_beta; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   PANTHER; PTHR19944:SF101; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN; 1.
DR   PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..106
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:SBL08075.1"
FT   NON_TER         138
FT                   /evidence="ECO:0000313|EMBL:SBL08075.1"
SQ   SEQUENCE   138 AA;  15383 MW;  F7CCA302F75B3055 CRC64;
     EPTVTISPSR TEALNHHNLL VCSVTDFYPA QIKVRWFRND QEETTGVVST PLIRNGDWTF
     QILVMLEMTP QRGDVYTCHV EHPSLQNPII VEWRAQSESA QSKMLSGIGG FVLGLIFLGL
     GLIIHHRSQK GPQGPPPA
//