ID   A0A1V9YH23_ACHHY        Unreviewed;       909 AA.
AC   A0A1V9YH23;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   29-MAY-2024, entry version 20.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN   ORFNames=ACHHYP_12421 {ECO:0000313|EMBL:OQR85025.1};
OS   Achlya hypogyna (Oomycete) (Protoachlya hypogyna).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Achlya.
OX   NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQR85025.1, ECO:0000313|Proteomes:UP000243579};
RN   [1] {ECO:0000313|EMBL:OQR85025.1, ECO:0000313|Proteomes:UP000243579}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQR85025.1,
RC   ECO:0000313|Proteomes:UP000243579};
RX   PubMed=25527045; DOI=10.1093/gbe/evu276;
RA   Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT   "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT   identify the ancestral oomycete secretome and reveal gene acquisitions by
RT   horizontal gene transfer.";
RL   Genome Biol. Evol. 7:120-135(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQR85025.1}.
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DR   EMBL; JNBR01001827; OQR85025.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V9YH23; -.
DR   STRING; 1202772.A0A1V9YH23; -.
DR   OrthoDB; 67255at2759; -.
DR   Proteomes; UP000243579; Unassembled WGS sequence.
DR   GO; GO:0038039; C:G protein-coupled receptor heterodimeric complex; IEA:TreeGrafter.
DR   GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:TreeGrafter.
DR   CDD; cd15047; 7tmC_GABA-B-like; 1.
DR   InterPro; IPR002455; GPCR3_GABA-B.
DR   InterPro; IPR017978; GPCR_3_C.
DR   PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR   PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243579};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..909
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012438645"
FT   TRANSMEM        613..636
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        648..667
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        679..700
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        721..742
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        771..795
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        807..829
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        835..856
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          617..859
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   REGION          870..909
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   909 AA;  99899 MW;  91A8C658EBFBA762 CRC64;
     MHRIAVLVAT TIMQSAATPT QSVMDAQRGT CLDAAWVTRT ATQYNLDPSA RDSTHRRLNP
     LLQPGMKIPR FSLRDTRMDL PDIFGSCMQS GEVIHGLGEL VFPNGSQAYA GVVNGTVVLE
     RNGWQSHDLS RQVLTILLQE VVGYGVSRFD TAGGLHCAER MSGERLGRCT PTHINSEVWT
     SGKLSTLNVY ANETAPTTNG YNGVGGLYTL TANVEEALKG PLSTQGTFSR PYSVDFWRDY
     FWSDEIINFY KATPANRAQL SDKSSCPDGT MGCLNACSKS HACTLAEAQG KPCMLIAMID
     ESYDPGYFQA IVANNKIPAY FCFGGYDGML DYVVRQMNAN GTVVFYEYEP DTFFFQYPGK
     FTRIAFPRSD PANVAQATGT FGELGYGNQT TNPLSTDFPT IPLMRYMSKV VTYDPFLNSF
     LSSMKLAPLD MNNIFTSFMT YSSNPAIPDP VFSAACTWIQ NNYLVWSNWV SALPLCSMQN
     NIQYTYAGCN SSSRVVTFAW NRPDPSNASL PYDCEGNIVV VPSPYTTSKT CAWLDANTKT
     WMNWLSSPPI CDASFYSYVV TECTATAQRN VFFNWLLPNP NDYAHSRECS GGVSLPANTT
     VDCDYVPTNS STYSGMVAFS IIVLVILVLS AILVIAFRDK PVIRRSQWHL LIVLLLGGMC
     MCIYVILGGG TPSDLLCGAR PVFASIGYTL AFGSLLLKSL RVYLVFHNKA FKKNVVTLAR
     MLHFLLGFLG IDVVILGVWY AVDFPGPTTS TSAAATFSGE VDHVACHSSS FIFPVLCIFW
     KAIITFIGLY VSFLIRHDDG DFQESIWIFS ASCVVLMGSL FMIPLAYLVS LPAATTYAFC
     SAVTLICTLM VMALMLGPKF ARLDRADYKS SGTTANGTKR TASVTSKPPS THSQMPMQSM
     KSPRETTQQ
//