ID A0A1V4U0X9_9EURY Unreviewed; 197 AA. AC A0A1V4U0X9; DT 07-JUN-2017, integrated into UniProtKB/TrEMBL. DT 07-JUN-2017, sequence version 1. DT 03-AUG-2022, entry version 13. DE RecName: Full=DNA-directed RNA polymerase subunit Rpo7 {ECO:0000256|HAMAP-Rule:MF_00865}; DE EC=2.7.7.6 {ECO:0000256|HAMAP-Rule:MF_00865}; DE AltName: Full=DNA-directed RNA polymerase subunit E {ECO:0000256|HAMAP-Rule:MF_00865}; GN Name=rpoE1 {ECO:0000313|EMBL:OPX66486.1}; GN Synonyms=rpo7 {ECO:0000256|HAMAP-Rule:MF_00865}, rpoE GN {ECO:0000256|HAMAP-Rule:MF_00865}; GN ORFNames=A4E36_02004 {ECO:0000313|EMBL:OPX66486.1}; OS Methanoregulaceae archaeon PtaB.Bin009. OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia; OC Methanomicrobiales; Methanoregulaceae. OX NCBI_TaxID=1811720 {ECO:0000313|EMBL:OPX66486.1, ECO:0000313|Proteomes:UP000289071}; RN [1] {ECO:0000313|EMBL:OPX66486.1, ECO:0000313|Proteomes:UP000289071} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PtaB.Bin009 {ECO:0000313|EMBL:OPX66486.1}; RA Nobu M.K., Narihiro T., Liu M., Kuroda K., Mei R., Liu W.-T.; RT "Diverse syntrophic catabolism for escaping thermodynamic limitations and RT driving niche segregation."; RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the CC transcription of DNA into RNA using the four ribonucleoside CC triphosphates as substrates. {ECO:0000256|HAMAP-Rule:MF_00865}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; CC EC=2.7.7.6; Evidence={ECO:0000256|HAMAP-Rule:MF_00865}; CC -!- SUBUNIT: Part of the RNA polymerase complex. Forms a stalk with Rpo4 CC that extends from the main structure. {ECO:0000256|HAMAP- CC Rule:MF_00865}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00865}. CC Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- DOMAIN: Forms 2 domains with an elongated structure; Rpo4 packs into CC the hinge region between the 2 domains. {ECO:0000256|HAMAP- CC Rule:MF_00865}. CC -!- SIMILARITY: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit CC family. {ECO:0000256|ARBA:ARBA00009307, ECO:0000256|HAMAP- CC Rule:MF_00865}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OPX66486.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MVQC01000128; OPX66486.1; -; Genomic_DNA. DR Proteomes; UP000289071; Unassembled WGS sequence. DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC. DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro. DR Gene3D; 2.40.50.140; -; 1. DR Gene3D; 3.30.1490.120; -; 1. DR HAMAP; MF_00865; RNApol_arch_Rpo7; 1. DR InterPro; IPR012340; NA-bd_OB-fold. DR InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf. DR InterPro; IPR004519; RNAP_E/RPC8. DR InterPro; IPR046399; RNApol_Rpo7. DR InterPro; IPR045113; Rpb7-like. DR InterPro; IPR005576; Rpb7-like_N. DR InterPro; IPR022967; S1_dom. DR InterPro; IPR003029; S1_domain. DR PANTHER; PTHR12709; PTHR12709; 1. DR Pfam; PF00575; S1; 1. DR Pfam; PF03876; SHS2_Rpb7-N; 1. DR SMART; SM00316; S1; 1. DR SUPFAM; SSF50249; SSF50249; 1. DR SUPFAM; SSF88798; SSF88798; 1. DR TIGRFAMs; TIGR00448; rpoE; 1. DR PROSITE; PS50126; S1; 1. PE 3: Inferred from homology; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00865}; KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478, KW ECO:0000256|HAMAP-Rule:MF_00865}; KW Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00865, KW ECO:0000313|EMBL:OPX66486.1}; KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP- KW Rule:MF_00865}; KW Transferase {ECO:0000256|HAMAP-Rule:MF_00865, ECO:0000313|EMBL:OPX66486.1}. FT DOMAIN 82..166 FT /note="S1 motif" FT /evidence="ECO:0000259|PROSITE:PS50126" FT REGION 178..197 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 197 AA; 22196 MW; 868F4563F4B2F2B1 CRC64; MYYKMQLADK VRVPPNRLGE DLTRVILDVL QEHLEGSIDK EIGIFISITK VLRIGEGEIV PGDGAVYYDV DFEAVVLRLA LQEVLEGLVV ETTSFGAFVS LGPIDAMLHV SQISDEYINY DEKNARLICQ ESKRFIGVGE PVRVRVVTLS LNEREPRDSK IGLTMRQSGL GTARWLEEDM LKEKEKEKEK GGERGSR //