ID A0A1V2SAP3_9BACI Unreviewed; 436 AA. AC A0A1V2SAP3; DT 07-JUN-2017, integrated into UniProtKB/TrEMBL. DT 07-JUN-2017, sequence version 1. DT 05-JUL-2017, entry version 2. DE RecName: Full=GTPase Der {ECO:0000256|HAMAP-Rule:MF_00195, ECO:0000256|RuleBase:RU004481, ECO:0000256|SAAS:SAAS00336749}; DE AltName: Full=GTP-binding protein EngA {ECO:0000256|HAMAP-Rule:MF_00195}; GN Name=der {ECO:0000256|HAMAP-Rule:MF_00195}; GN ORFNames=BLX87_18470 {ECO:0000313|EMBL:ONK21894.1}; OS Bacillus sp. VT-16-64. OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. OX NCBI_TaxID=1917019 {ECO:0000313|EMBL:ONK21894.1, ECO:0000313|Proteomes:UP000188748}; RN [1] {ECO:0000313|EMBL:ONK21894.1, ECO:0000313|Proteomes:UP000188748} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VT-16-64 {ECO:0000313|EMBL:ONK21894.1, RC ECO:0000313|Proteomes:UP000188748}; RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.; RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: GTPase that plays an essential role in the late steps of CC ribosome biogenesis. {ECO:0000256|HAMAP-Rule:MF_00195, CC ECO:0000256|RuleBase:RU004481, ECO:0000256|SAAS:SAAS00534042}. CC -!- SUBUNIT: Associates with the 50S ribosomal subunit. CC {ECO:0000256|HAMAP-Rule:MF_00195, ECO:0000256|SAAS:SAAS00336742}. CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- CC like GTPase superfamily. EngA (Der) GTPase family. CC {ECO:0000256|HAMAP-Rule:MF_00195, ECO:0000256|PROSITE- CC ProRule:PRU01049, ECO:0000256|RuleBase:RU004481, CC ECO:0000256|SAAS:SAAS00534053}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:ONK21894.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MSRF01000257; ONK21894.1; -; Genomic_DNA. DR RefSeq; WP_077113305.1; NZ_MSRF01000257.1. DR Proteomes; UP000188748; Unassembled WGS sequence. DR Gene3D; 3.30.300.20; -; 1. DR HAMAP; MF_00195; GTPase_Der; 1. DR InterPro; IPR031166; G_ENGA. DR InterPro; IPR016484; GTP-bd_EngA. DR InterPro; IPR006073; GTP_binding_domain. DR InterPro; IPR032859; KH_dom-like. DR InterPro; IPR015946; KH_dom-like_a/b. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR005225; Small_GTP-bd_dom. DR Pfam; PF14714; KH_dom-like; 1. DR Pfam; PF01926; MMR_HSR1; 2. DR PIRSF; PIRSF006485; GTP-binding_EngA; 1. DR PRINTS; PR00326; GTP1OBG. DR SUPFAM; SSF52540; SSF52540; 2. DR TIGRFAMs; TIGR03594; GTPase_EngA; 1. DR TIGRFAMs; TIGR00231; small_GTP; 2. DR PROSITE; PS51712; G_ENGA; 2. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000188748}; KW GTP-binding {ECO:0000256|HAMAP-Rule:MF_00195, KW ECO:0000256|RuleBase:RU004481, ECO:0000256|SAAS:SAAS00038177}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00195, KW ECO:0000256|RuleBase:RU004481, ECO:0000256|SAAS:SAAS00038187}; KW Repeat {ECO:0000256|RuleBase:RU004481, ECO:0000256|SAAS:SAAS00038179}; KW Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_00195, KW ECO:0000256|SAAS:SAAS00038183}. FT DOMAIN 4 167 EngA-type G (guanine nucleotide-binding). FT {ECO:0000259|PROSITE:PS51712}. FT DOMAIN 176 351 EngA-type G (guanine nucleotide-binding). FT {ECO:0000259|PROSITE:PS51712}. FT NP_BIND 10 17 GTP 1. {ECO:0000256|HAMAP-Rule:MF_00195}. FT NP_BIND 57 61 GTP 1. {ECO:0000256|HAMAP-Rule:MF_00195}. FT NP_BIND 119 122 GTP 1. {ECO:0000256|HAMAP-Rule:MF_00195}. FT NP_BIND 182 189 GTP 2. {ECO:0000256|HAMAP-Rule:MF_00195}. FT NP_BIND 229 233 GTP 2. {ECO:0000256|HAMAP-Rule:MF_00195}. FT NP_BIND 294 297 GTP 2. {ECO:0000256|HAMAP-Rule:MF_00195}. SQ SEQUENCE 436 AA; 48760 MW; FF73E205539C4A3A CRC64; MGMPTVAIVG RPNVGKSTIF NRIVGERISI VEDEPGVTRD RIYGTGEWLT TYFHVIDTGG IDIGDAPFLE EVRQQAEIAI EEADVIIFIV NSREGVTSAD EEVAKILFRS KKPVVLAVNK VDNPEMRSQI YDFYSLGFGE PFPISGSHGL GLGDLLDEVI KHFPADHGDP YDEDVIKFSL IGRPNVGKSS LVNALLGEER VIVSPIAGTT RDAVDTPYIV DGQEYVIIDT AGMRKRGKVY ESTEKYSVLR ALKAIERSDV VLVVLDGEEG IREQDKRIAG YAHEAGRAII IVVNKWDAVE KDEKTMRNFE EKIRDQFQFL DYAPIVFLSA KTKKRIGTLL PAIQMASENH ARRVQSSVLN EVILDAAAMN PAPADKGKRL KVYYATQVSV KPPTFVVFVN EPELMHFSYE RFLRNTIRQA FEFEGTPLKI IARKRK //