ID A0A1T5AAP1_9BACT Unreviewed; 526 AA. AC A0A1T5AAP1; DT 10-MAY-2017, integrated into UniProtKB/TrEMBL. DT 10-MAY-2017, sequence version 1. DT 28-JUN-2023, entry version 21. DE SubName: Full=Beta-xylosidase {ECO:0000313|EMBL:SKB32008.1}; GN ORFNames=SAMN03080601_00181 {ECO:0000313|EMBL:SKB32008.1}; OS Alkalitalea saponilacus. OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae; OC Alkalitalea. OX NCBI_TaxID=889453 {ECO:0000313|EMBL:SKB32008.1, ECO:0000313|Proteomes:UP000191055}; RN [1] {ECO:0000313|EMBL:SKB32008.1, ECO:0000313|Proteomes:UP000191055} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 24412 {ECO:0000313|EMBL:SKB32008.1, RC ECO:0000313|Proteomes:UP000191055}; RA Peterson S.W.; RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family. CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FUYV01000001; SKB32008.1; -; Genomic_DNA. DR AlphaFoldDB; A0A1T5AAP1; -. DR STRING; 889453.SAMN03080601_00181; -. DR EnsemblBacteria; SKB32008; SKB32008; SAMN03080601_00181. DR KEGG; asx:CDL62_06280; -. DR OrthoDB; 9801455at2; -. DR Proteomes; UP000191055; Unassembled WGS sequence. DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR CDD; cd09001; GH43_FsAxh1-like; 1. DR Gene3D; 2.60.120.200; -; 1. DR InterPro; IPR013320; ConA-like_dom_sf. DR InterPro; IPR041542; GH43_C2. DR InterPro; IPR006710; Glyco_hydro_43. DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf. DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1. DR PANTHER; PTHR42812:SF2; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED; 1. DR Pfam; PF17851; GH43_C2; 1. DR Pfam; PF04616; Glyco_hydro_43; 1. DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1. DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1. DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1. PE 3: Inferred from homology; KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187}; KW Reference proteome {ECO:0000313|Proteomes:UP000191055}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..21 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 22..526 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5012188375" FT DOMAIN 335..519 FT /note="Beta-xylosidase C-terminal Concanavalin A-like" FT /evidence="ECO:0000259|Pfam:PF17851" FT ACT_SITE 41 FT /note="Proton acceptor" FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1" FT ACT_SITE 209 FT /note="Proton donor" FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1" FT SITE 152 FT /note="Important for catalytic activity, responsible for FT pKa modulation of the active site Glu and correct FT orientation of both the proton donor and substrate" FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2" SQ SEQUENCE 526 AA; 58988 MW; 96C0C09434235E18 CRC64; MKTLLSLVLF VFLLAGCKSQ ANIEEARDKA TNPVVWADIP DMSIVLVDDT YYMASTTMHM SPGLPIMKSK DLVNWEIVSY AYDILVDNDR MSLRNGESAY GNGSWAPSLR YHNGVFYAST FSATSGKTHI YKTTDIENGT WEEISFRPSI HDHSLFFDDD GKVYLIAGVG RITMVELKED LSGVKEGSEV LLIENASAPA GDNIMLPAEG SQMFKFDGKY YLFNITWVRG GMRKVIIHKA DQITGPYEGR LALRDRGIAQ GGLIETTEGD WVAFLFRDFG SVGRIPYMVP AKWEDGWPVL GVDGVVPDTL DIPVKNINAA GIVASDNFER ESGDNSMPLV WQWNHNPVNE YWTLQERKGY FRLKTSRVDE NVLQARNTLT QRTFGPESSA STVIDVSNMK DGDFAGMIAL QRRYGFVGVS RDGNSTSIIM VSNESEEPVE LERIELNQDK VYLKIACDYN DRNDKAYFYY SLDGQAWTEI GESLQMAYTL PHFMGYRFGL FNYATKSVGG YVDFGHFEIS DSMGGN //