ID A0A1S2N0I0_9MICC Unreviewed; 508 AA. AC A0A1S2N0I0; DT 12-APR-2017, integrated into UniProtKB/TrEMBL. DT 12-APR-2017, sequence version 1. DT 14-DEC-2022, entry version 12. DE SubName: Full=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase {ECO:0000313|EMBL:OIJ35513.1}; GN ORFNames=BK826_07170 {ECO:0000313|EMBL:OIJ35513.1}; OS Rothia kristinae. OC Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Rothia. OX NCBI_TaxID=37923 {ECO:0000313|EMBL:OIJ35513.1, ECO:0000313|Proteomes:UP000179540}; RN [1] {ECO:0000313|EMBL:OIJ35513.1, ECO:0000313|Proteomes:UP000179540} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LCT-H5 {ECO:0000313|EMBL:OIJ35513.1, RC ECO:0000313|Proteomes:UP000179540}; RA Huang B.; RT "Draft genome sequence of strain LCT isolated from the Shenzhou X RT spacecraft of China."; RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family. CC {ECO:0000256|RuleBase:RU003345}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OIJ35513.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MODZ01000008; OIJ35513.1; -; Genomic_DNA. DR RefSeq; WP_075515024.1; NZ_MODZ01000008.1. DR AlphaFoldDB; A0A1S2N0I0; -. DR EnsemblBacteria; OIJ35513; OIJ35513; BK826_07170. DR Proteomes; UP000179540; Unassembled WGS sequence. DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. DR Gene3D; 3.40.309.10; -; 1. DR Gene3D; 3.40.605.10; -; 1. DR InterPro; IPR016161; Ald_DH/histidinol_DH. DR InterPro; IPR016163; Ald_DH_C. DR InterPro; IPR016160; Ald_DH_CS_CYS. DR InterPro; IPR029510; Ald_DH_CS_GLU. DR InterPro; IPR016162; Ald_DH_N. DR InterPro; IPR015590; Aldehyde_DH_dom. DR Pfam; PF00171; Aldedh; 1. DR SUPFAM; SSF53720; ALDH-like; 1. DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1. DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1. PE 3: Inferred from homology; KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, KW ECO:0000256|RuleBase:RU003345}. FT DOMAIN 31..492 FT /note="Aldedh" FT /evidence="ECO:0000259|Pfam:PF00171" FT ACT_SITE 268 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007" FT ACT_SITE 302 FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10008" SQ SEQUENCE 508 AA; 55256 MW; D0D586DE573D4507 CRC64; MTESIEQIQQ QARPADLPEV LRHYIGGEFV DSLDGETFDV LDPVTNRPYI RAASGKKADV DAAVAAAKEA FENGPWPGML PRERSRVLHR IADIVESRGE ALAAMESYDS GLPITQALGQ ARRAAENFRF FADLIVAQHD DAFKVPGRQV NYVNRKPKGV AGLITPWNTP FMLESWKLAP AIATGNTVVL KPAEFTPLSA SLWPGIFEEA GLPTGVFNLV NGFGEEGYAG DSLVRHPDVP LISFTGESRT GQIIFANAAP HLKGLSMELG GKSPAVVFED ADLDTAIDAT IFGVFSLNGE RCTAGSRILV QRGIYDEFVS RYAAQAERVK VGLPSEKTTE VGALVHPEHF EKVMSYVQIG RTEARLVAGG GRPEQFPEGN FIRPTVFADV APEARIFQEE IFGPVVAITP FDTEEEALAL ANDTKYGLAA YIWTNDLKRA HTFAQATQAG MVWLNSNNVR DLRTPFGGVK ASGLGHEGGY RSIDFYTDSQ AVHINLGEVH NPVFGKQV //