ID   A0A1P8ARM8_ARATH        Unreviewed;       434 AA.
AC   A0A1P8ARM8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-FEB-2025, entry version 36.
DE   SubName: Full=Cytochrome P450, family 722, subfamily A, polypeptide 1 {ECO:0000313|EMBL:ANM59306.1};
GN   Name=CYP722A1 {ECO:0000313|EMBL:ANM59306.1,
GN   ECO:0000313|TAIR:AT1G19630};
GN   Synonyms=cytochrome P450 {ECO:0000313|EMBL:ANM59306.1}, family 722
GN   {ECO:0000313|EMBL:ANM59306.1}, polypeptide 1
GN   {ECO:0000313|EMBL:ANM59306.1}, subfamily A
GN   {ECO:0000313|EMBL:ANM59306.1};
GN   OrderedLocusNames=At1g19630 {ECO:0000313|Araport:AT1G19630,
GN   ECO:0000313|EMBL:ANM59306.1};
GN   ORFNames=F14P1.4 {ECO:0000313|EMBL:ANM59306.1}, F14P1_4
GN   {ECO:0000313|EMBL:ANM59306.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM59306.1, ECO:0000313|Proteomes:UP000006548};
RN   [1] {ECO:0000313|EMBL:ANM59306.1, ECO:0000313|Proteomes:UP000006548}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2] {ECO:0000313|Proteomes:UP000006548}
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617}.
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DR   EMBL; CP002684; ANM59306.1; -; Genomic_DNA.
DR   RefSeq; NP_001321673.1; NM_001332399.1.
DR   AlphaFoldDB; A0A1P8ARM8; -.
DR   SMR; A0A1P8ARM8; -.
DR   EnsemblPlants; AT1G19630.2; AT1G19630.2; AT1G19630.
DR   GeneID; 838550; -.
DR   Gramene; AT1G19630.2; AT1G19630.2; AT1G19630.
DR   KEGG; ath:AT1G19630; -.
DR   Araport; AT1G19630; -.
DR   TAIR; AT1G19630; CYP722A1.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; A0A1P8ARM8; baseline and differential.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002403; Cyt_P450_E_grp-IV.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24286; CYTOCHROME P450 26; 1.
DR   PANTHER; PTHR24286:SF189; CYTOCHROME P450, FAMILY 722, SUBFAMILY A, POLYPEPTIDE 1; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00465; EP450IV.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..434
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010202496"
SQ   SEQUENCE   434 AA;  49935 MW;  F3430C659B754DCC CRC64;
     MEHLCLCLVL CAAMLTLGKF LKIMFQDRKK STAGVPPGSD GFPVIGETLQ FMLSVNSGKG
     FYEFVRSRRI RYGSCFRTSL FGETHVFLST TESARLVLNN DSGMFTKRYI KSIGELVGDR
     SLLCAPQHHH KILRSRLINL FSKRSTALMV RHFDELVVDA LGGWEHRGTV VLLTDLLQIT
     FKAMCKMLVS LEKEEELGSM QRDVGFVCEA MLAFPLNLPW TRFHKGIMAR GRVMEMLEKI
     IRERRNEINS HNNHHEDFLQ QLLAVDNDTP QLTDAEIKDN ILTMIIAGQD TTASALTWMV
     KYLGENQKVL DILIEEQSQI TKKASNKPFL ELEDLSEMPY ASKMVKESLR MASVVPWFPR
     LVLQDCEMEG YKIKKGWNIN IDARSIHLDP TVYSEPHKFN PLRFEVNKPQ FKVNILKFTV
     PLFKCFWFYL INLN
//