ID A0A1N7N277_9BACI Unreviewed; 617 AA. AC A0A1N7N277; DT 15-MAR-2017, integrated into UniProtKB/TrEMBL. DT 15-MAR-2017, sequence version 1. DT 26-FEB-2020, entry version 12. DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:SIS92301.1}; GN ORFNames=SAMN05421758_11061 {ECO:0000313|EMBL:SIS92301.1}; OS Salimicrobium salexigens. OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Salimicrobium. OX NCBI_TaxID=908941 {ECO:0000313|EMBL:SIS92301.1, ECO:0000313|Proteomes:UP000199777}; RN [1] {ECO:0000313|EMBL:SIS92301.1, ECO:0000313|Proteomes:UP000199777} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 22782 {ECO:0000313|EMBL:SIS92301.1, RC ECO:0000313|Proteomes:UP000199777}; RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.; RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|SAAS:SAAS01126420}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FTOK01000010; SIS92301.1; -; Genomic_DNA. DR RefSeq; WP_076572447.1; NZ_FTOK01000010.1. DR Proteomes; UP000199777; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro. DR CDD; cd06225; HAMP; 1. DR CDD; cd00082; HisKA; 1. DR CDD; cd00130; PAS; 1. DR Gene3D; 3.30.565.10; -; 1. DR InterPro; IPR003660; HAMP_dom. DR InterPro; IPR003594; HATPase_C. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR003661; HisK_dim/P. DR InterPro; IPR036097; HisK_dim/P_sf. DR InterPro; IPR000014; PAS. DR InterPro; IPR000700; PAS-assoc_C. DR InterPro; IPR035965; PAS-like_dom_sf. DR InterPro; IPR013767; PAS_fold. DR InterPro; IPR004358; Sig_transdc_His_kin-like_C. DR Pfam; PF00672; HAMP; 1. DR Pfam; PF02518; HATPase_c; 1. DR Pfam; PF00512; HisKA; 1. DR Pfam; PF00989; PAS; 1. DR PRINTS; PR00344; BCTRLSENSOR. DR SMART; SM00304; HAMP; 1. DR SMART; SM00387; HATPase_c; 1. DR SMART; SM00388; HisKA; 1. DR SMART; SM00091; PAS; 1. DR SUPFAM; SSF47384; SSF47384; 1. DR SUPFAM; SSF55785; SSF55785; 1. DR SUPFAM; SSF55874; SSF55874; 1. DR TIGRFAMs; TIGR00229; sensory_box; 1. DR PROSITE; PS50885; HAMP; 1. DR PROSITE; PS50109; HIS_KIN; 1. DR PROSITE; PS50113; PAC; 1. DR PROSITE; PS50112; PAS; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|SAAS:SAAS01243487}; KW Kinase {ECO:0000256|SAAS:SAAS00529081, ECO:0000313|EMBL:SIS92301.1}; KW Membrane {ECO:0000256|SAAS:SAAS00833905, ECO:0000256|SAM:Phobius}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS01243463}; KW Transferase {ECO:0000256|SAAS:SAAS00529055}; KW Transmembrane {ECO:0000256|SAAS:SAAS00833930, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00833995, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 12..34 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 193..216 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 214..266 FT /note="HAMP" FT /evidence="ECO:0000259|PROSITE:PS50885" FT DOMAIN 271..327 FT /note="PAS" FT /evidence="ECO:0000259|PROSITE:PS50112" FT DOMAIN 335..389 FT /note="PAC" FT /evidence="ECO:0000259|PROSITE:PS50113" FT DOMAIN 393..610 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" SQ SEQUENCE 617 AA; 69616 MW; 67DFD10C83BDC440 CRC64; MSKVGFFQSV RLKLIIVYIL LILLGLQVIG AYFVDRLEAQ LQNNFTESVE SRLDALAFNI QQAFEEDRTE EDPSLESDVQ SILNSFNEGY VRNEIRQLQV IEEGSNVVIA AYASGDATPQ ANVGKKTTNP DVLSAFLLQD QSSPETRVDS ETGQRLWVGT RTITNDVDET VAAIYFEADM SPVYEELQDI NTIFANGTVI SIIVTAILGI IVAGTITKPL IEMRRQAQIM ATGDFSQKVN VHGNDEIGQL GHTFNDLNDK LKISQATTEG ERRKLSSVLS HMSDGVIATD RLGIITLMNA PASHLIGQRF EQVQGKPLID VLGLEDQVSS AKEMEDLDSV IVDMSTNDQH LLLKANFSVV QDEHYEMNGF ITVISDVTEQ QRADQERREF VSNVSHELRT PLTTMRSYLE ALNDGAWRDE EIAPRFLDVT QNETDRMIRL VNDLLQLTKM DHKESSFYKE KVEFVSFLEQ IIERFEMNKR EDIQFSKQLP SDNVYVWLDK DKVTQVLDNV ISNATKYSPE GGTIHFAVKR VRQKLQVSIK DEGLGMPAHT VEKIFDRFYR VDKARSREIG GTGLGLAIAR EIIEAHHGEI WAESQEGKGT TVFFTLPLMR QKRRGNK //