ID A0A1L8FX02_XENLA Unreviewed; 547 AA. AC A0A1L8FX02; DT 15-MAR-2017, integrated into UniProtKB/TrEMBL. DT 15-MAR-2017, sequence version 1. DT 02-OCT-2024, entry version 31. DE SubName: Full=Sodium- and chloride-dependent transporter XTRP3A isoform X2 {ECO:0000313|RefSeq:XP_018123097.1}; GN Name=slc6a20.L {ECO:0000313|RefSeq:XP_018123097.1, GN ECO:0000313|Xenbase:XB-GENE-17337236}; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus. OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018123097.1}; RN [1] {ECO:0000313|RefSeq:XP_018123097.1} RP IDENTIFICATION. RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018123097.1}; RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018123097.1}; RG RefSeq; RL Submitted (JUN-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_018123097.1; XM_018267608.2. DR AlphaFoldDB; A0A1L8FX02; -. DR STRING; 8355.A0A1L8FX02; -. DR PaxDb; 8355-A0A1L8FX02; -. DR GeneID; 108719021; -. DR KEGG; xla:108719021; -. DR CTD; 108719021; -. DR Xenbase; XB-GENE-17337236; slc6a20.L. DR OMA; FNNINHR; -. DR OrthoDB; 3084493at2759; -. DR Proteomes; UP000186698; Chromosome 6L. DR Bgee; 108719021; Expressed in camera-type eye and 4 other cell types or tissues. DR GO; GO:0005886; C:plasma membrane; IEA:InterPro. DR InterPro; IPR000175; Na/ntran_symport. DR InterPro; IPR002438; Neutral_aa_SLC6. DR InterPro; IPR037272; SNS_sf. DR PANTHER; PTHR11616:SF44; SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3; 1. DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1. DR Pfam; PF00209; SNF; 1. DR PRINTS; PR00176; NANEUSMPORT. DR PRINTS; PR01206; ORPHTRNSPORT. DR SUPFAM; SSF161070; SNF-like; 1. DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1. PE 4: Predicted; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR600175-1}; KW Reference proteome {ECO:0000313|Proteomes:UP000186698}; KW Sodium {ECO:0000256|PIRSR:PIRSR600175-1}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}; KW Transport {ECO:0000256|ARBA:ARBA00022448}. FT BINDING 204 FT /ligand="Na(+)" FT /ligand_id="ChEBI:CHEBI:29101" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR600175-1" FT BINDING 236 FT /ligand="Na(+)" FT /ligand_id="ChEBI:CHEBI:29101" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR600175-1" FT BINDING 355 FT /ligand="Na(+)" FT /ligand_id="ChEBI:CHEBI:29101" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR600175-1" FT BINDING 359 FT /ligand="Na(+)" FT /ligand_id="ChEBI:CHEBI:29101" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR600175-1" SQ SEQUENCE 547 AA; 61190 MW; 6B6025A763EB2465 CRC64; MIMLILEGMP LLYLELAVGQ LIRQGSIGAW KTISPYLGGV GIASVVVSFF LCIYYNVINA WAFWYLFHSF QEPLPWSNCP LNNNMSAYIE ECEISSPTQY FWYRETINIS PSIAHSGGIQ WEQAVCLILS WLAVYVCILR GTESTGKVVY VTASLPYLVL LIYLVRGLTL HGAANGLAFM FTPKLDQLAN PKTWINAATQ IFFSLGLGFG SLIAFASYNE PNNNCERHAI IVSLINSGTS IFASIVTFSI YGFKATYNYE NCISRDILLL TNTFDLEEGS ITAENLGDMK NYLNATFHQE FSAIVPQIRN CSLEKELSTA VQGTGLAFIV YTEAIKNMEV SQLWSVIYFL MLLMLGLGSM LGNTAAILTP LTDSKFISKH LPKEAVSGLL CFTCCIIGLI FTLESGSYWF DIFNDYSVTL SLLLIVFAEI IGICYVYGLR RFEKDLAIMT GRKLSWYWKI MWGFASPLLI ISLFIFYLTD YIMAGTLQYK AWDATLGQLV TKDYPTYALV VIGLLVVAPF CCITVVAIVN IVTSRIKRKE NCNTIQT //