ID A0A1L7B6G7_MEGAM Unreviewed; 706 AA. AC A0A1L7B6G7; DT 15-MAR-2017, integrated into UniProtKB/TrEMBL. DT 15-MAR-2017, sequence version 1. DT 30-AUG-2017, entry version 4. DE SubName: Full=Interleukin-1 receptor-associated kinase 1 {ECO:0000313|EMBL:APT68702.1}; DE EC=2.7.11.1 {ECO:0000313|EMBL:APT68702.1}; GN Name=IRAK1 {ECO:0000313|EMBL:APT68702.1}; OS Megalobrama amblycephala (Chinese blunt snout bream) (Brema carp). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Megalobrama. OX NCBI_TaxID=75352 {ECO:0000313|EMBL:APT68702.1}; RN [1] {ECO:0000313|EMBL:APT68702.1} RP NUCLEOTIDE SEQUENCE. RA Jakovlic I., Tran N.T., Wang W.; RT "Cloning, characterisation and expression of IRAK1 in blunt snout RT bream (Megalobrama amblycephala)."; RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KU361203; APT68702.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR CDD; cd08794; Death_IRAK1; 1. DR InterPro; IPR011029; DEATH-like_dom. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR035533; Death_IRAK1. DR InterPro; IPR035536; IRAK1. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR PANTHER; PTHR24419:SF29; PTHR24419:SF29; 1. DR Pfam; PF00531; Death; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR SUPFAM; SSF56112; SSF56112; 2. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 4: Predicted; KW Kinase {ECO:0000313|EMBL:APT68702.1}; KW Receptor {ECO:0000313|EMBL:APT68702.1}; KW Transferase {ECO:0000313|EMBL:APT68702.1}. FT DOMAIN 190 498 Protein kinase. {ECO:0000259|PROSITE: FT PS50011}. SQ SEQUENCE 706 AA; 79268 MW; 0BF1CC0F05D754B6 CRC64; MSGVEFEREF LYNLPASVMS HFTRVMDSLS HSDWILFASH VISDQTELRL LEQSPRRTDI LMHKWGCRNG TVGELLQILE GLQWFRPRDI ILECRRIPQS RLERRSPSPV PPSTACQTST VSFIKEFLPV HEIRPLPKPS PPPPDMDSIS SRTSNIAEKC PSKNRVDPPP LYSTAMSWPF EEIQRGTCNF SPCKQIGEGG FGHVYQAVMR NTEFAVKKLK EDSHLDWDVV KESFRTEVEK LSQYRHPNIM DFVGYSIDRQ IYCLIYVYMP NGSLEDRLRC EDSNALSWSQ RVNVLLGTAK AIQYLHSCSP ALIHGDIKSS NILLGDHLEP KLGDFGLARF CRSPSKTPGK TSTVAHTATV RGTLAYLPEE YLKDGQLGVE IDVYSFGVVI LEVLTGRQAL EVDGQSKTVY LKDLVKEEED DGRSFSKGKH SRELSYVNAA ENICRKHLDP RLMTKDTPTP HGSMEISQMA CRCLERRRKK RPPMTEVFKA LQDVHSGLKT SGRLTTVRLS PVSSHPSTPE PLRSNDSSLD SLTHQFSKLH PQENTYPYLQ KPVFPTLNSV MTQSSCSVSE LNAESWASQS SGMPCESDES QGFSQYLTSH CSRPQSTSCG ACGVQSTEIS SSLEENPSQS SPNEDFSDQK AFINPVRQRL VQKMELYEEG RILTSDLLSS GDSLYRGMNA QTREPEESDE FASETSGVDM QSPAAV //