ID A0A1L1SVJ3_MOUSE Unreviewed; 358 AA. AC A0A1L1SVJ3; DT 15-FEB-2017, integrated into UniProtKB/TrEMBL. DT 15-FEB-2017, sequence version 1. DT 07-NOV-2018, entry version 9. DE SubName: Full=C-X-C chemokine receptor type 6 {ECO:0000313|Ensembl:ENSMUSP00000151182}; GN Name=Cxcr6 {ECO:0000313|Ensembl:ENSMUSP00000151182, GN ECO:0000313|MGI:MGI:1934582}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000151182, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000151182, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000151182, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000151182} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000151182}; RG Ensembl; RL Submitted (DEC-2016) to UniProtKB. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00594957}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC165425; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000216072; ENSMUSP00000151182; ENSMUSG00000048521. DR MGI; MGI:1934582; Cxcr6. DR GeneTree; ENSGT00930000150843; -. DR Proteomes; UP000000589; Chromosome 9. DR ExpressionAtlas; A0A1L1SVJ3; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0016494; F:C-X-C chemokine receptor activity; IEA:InterPro. DR GO; GO:0015026; F:coreceptor activity; IEA:InterPro. DR GO; GO:0006935; P:chemotaxis; IEA:InterPro. DR GO; GO:0006954; P:inflammatory response; IEA:InterPro. DR CDD; cd15173; 7tmA_CXCR6; 1. DR InterPro; IPR002235; Chemokine_CXCR6. DR InterPro; IPR000355; Chemokine_rcpt. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR PANTHER; PTHR10489:SF705; PTHR10489:SF705; 1. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00657; CCCHEMOKINER. DR PRINTS; PR01105; CXCCHMKINER6. DR PRINTS; PR00237; GPCRRHODOPSN. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00522141}; KW Membrane {ECO:0000256|SAAS:SAAS00522119, ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|EPD:A0A1L1SVJ3}; KW Receptor {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00522103}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transducer {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00522135}; KW Transmembrane {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00522128, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00522140, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 48 74 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 86 107 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 127 150 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 162 185 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 205 227 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 248 271 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 291 311 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 64 304 G_PROTEIN_RECEP_F1_2. FT {ECO:0000259|PROSITE:PS50262}. SQ SEQUENCE 358 AA; 41202 MW; 4D886319BCEE59BE CRC64; MFAPTDAMDD GHQESALYDG HYEGDFWLFN NSSDNSQENK RFLKFKEVFL PCVYLVVFVF GLLGNSLVLI IYIFYQKLRT LTDVFLLNLP LADLVFVCTL PFWAYAGTYE WVFGTVMCKT LRGMYTMNFY VSMLTLTCIT VDRFIVVVQA TKAFNRQAKW KIWGQVICLL IWVVSLLVSL PQIIYGHVQD IDKLICQYHS EEISTMVLVI QMTLGFFLPL LTMILCYSGI IKTLLHARNF QKHKSLKIIF LVVAVFLLTQ TPFNLAMLIQ STSWEYYTIT SFKYAIVVTE AIAYFRACLN PVLYAFVGLK FRKNVWKLMK DIGCLSHLGV SSQWKSSEDS SKTCSASHNV ETTSMFQL //