ID   A0A1I6FRM4_9FLAO        Unreviewed;       293 AA.
AC   A0A1I6FRM4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   07-APR-2021, entry version 9.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|ARBA:ARBA00021872};
DE            EC=4.2.1.51 {ECO:0000256|ARBA:ARBA00013147};
GN   ORFNames=SAMN04490243_0509 {ECO:0000313|EMBL:SFR32548.1};
OS   Robiginitalea myxolifaciens.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Robiginitalea.
OX   NCBI_TaxID=400055 {ECO:0000313|EMBL:SFR32548.1, ECO:0000313|Proteomes:UP000199534};
RN   [1] {ECO:0000313|EMBL:SFR32548.1, ECO:0000313|Proteomes:UP000199534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21019 {ECO:0000313|EMBL:SFR32548.1,
RC   ECO:0000313|Proteomes:UP000199534};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934; EC=4.2.1.51;
CC         Evidence={ECO:0000256|ARBA:ARBA00000913};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00004741}.
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DR   EMBL; FOYQ01000001; SFR32548.1; -; Genomic_DNA.
DR   EnsemblBacteria; SFR32548; SFR32548; SAMN04490243_0509.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000199534; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Phenylalanine biosynthesis {ECO:0000256|ARBA:ARBA00023222};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199534}.
FT   DOMAIN          22..199
FT                   /note="Prephenate dehydratase"
FT                   /evidence="ECO:0000259|PROSITE:PS51171"
FT   DOMAIN          213..289
FT                   /note="ACT"
FT                   /evidence="ECO:0000259|PROSITE:PS51671"
FT   SITE            192
FT                   /note="Essential for prephenate dehydratase activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001500-2"
SQ   SEQUENCE   293 AA;  32870 MW;  05819FC6A4DE1F96 CRC64;
     MSGPGIEFLV KDESANKVET QKIAIQGIPG SNHHMVAEAF YGKEVALHPC LSFHELVDSL
     LEGEAGQGIM AIENSIAGSI IPNYALIHDN SLHIIGEYYL NVHHHLMALP GQQLEAIREV
     HSHPMALLQC REYLKKQKGL KMVEDVDTAE TARRIQQQNL QGIAAIAPVR AAELYGLEIL
     SSEIQTIKNN ATRFVILKRE NKVLPQEEID KASIRFLTDH KRGSLATVLN VMSDCNLNLT
     KIQSLPVIET PWKYAFFVDI TFEEYAHFAK AKSLLEIMSE DFQVLGEYKN ARK
//