ID   A0A1H5SQ85_9CLOT        Unreviewed;       450 AA.
AC   A0A1H5SQ85;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   15-MAR-2017, entry version 3.
DE   RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|HAMAP-Rule:MF_00473};
DE            Short=GPI {ECO:0000256|HAMAP-Rule:MF_00473};
DE            EC=5.3.1.9 {ECO:0000256|HAMAP-Rule:MF_00473};
DE   AltName: Full=Phosphoglucose isomerase {ECO:0000256|HAMAP-Rule:MF_00473};
DE            Short=PGI {ECO:0000256|HAMAP-Rule:MF_00473};
DE   AltName: Full=Phosphohexose isomerase {ECO:0000256|HAMAP-Rule:MF_00473};
DE            Short=PHI {ECO:0000256|HAMAP-Rule:MF_00473};
GN   Name=pgi {ECO:0000256|HAMAP-Rule:MF_00473};
GN   ORFNames=SAMN05660865_00428 {ECO:0000313|EMBL:SEF52128.1};
OS   Caloramator fervidus.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Caloramator.
OX   NCBI_TaxID=29344 {ECO:0000313|EMBL:SEF52128.1};
RN   [1] {ECO:0000313|EMBL:SEF52128.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 5463 {ECO:0000313|EMBL:SEF52128.1};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate. {ECO:0000256|HAMAP-Rule:MF_00473,
CC       ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00674949}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00473}.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC       {ECO:0000256|HAMAP-Rule:MF_00473, ECO:0000256|RuleBase:RU000612,
CC       ECO:0000256|SAAS:SAAS00674955}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00473,
CC       ECO:0000256|SAAS:SAAS00674947}.
CC   -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|HAMAP-
CC       Rule:MF_00473, ECO:0000256|RuleBase:RU000612,
CC       ECO:0000256|SAAS:SAAS00674959}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00473}.
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DR   EMBL; FNUK01000003; SEF52128.1; -; Genomic_DNA.
DR   UniPathway; UPA00109; UER00181.
DR   UniPathway; UPA00138; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00473; G6P_isomerase; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; PTHR11469; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
DR   PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00473,
KW   ECO:0000256|SAAS:SAAS00674954};
KW   Gluconeogenesis {ECO:0000256|HAMAP-Rule:MF_00473,
KW   ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00674948};
KW   Glycolysis {ECO:0000256|HAMAP-Rule:MF_00473,
KW   ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00674958};
KW   Isomerase {ECO:0000256|HAMAP-Rule:MF_00473,
KW   ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00674960,
KW   ECO:0000313|EMBL:SEF52128.1}.
FT   ACT_SITE    425    425       {ECO:0000256|HAMAP-Rule:MF_00473}.
SQ   SEQUENCE   450 AA;  50977 MW;  8C7B11362230AF45 CRC64;
     MKNITLDYSK VLPFVKVEEI NNLESQIKDA HEKLHNKTGP GSDFLGWVTL PRDYDKDEFK
     RILRAAERIK ENSDVFVVIG IGGSYLGARA AIEMLNHTFY NILPKNKRKT PEIYFVGNNI
     SPVYMHDLLE ILEGKDISVN VISKSGTTTE PAIAFRILKE YMERKYGKEE ARKRIYATTD
     KSKGALRKLA EEEGYETFVI PDDVGGRYSV LTAVGLLPIA VSGVDIKEII KGAQDGMDEY
     SNLDVFNNAA YLYAAIRNIL YRKGKTVEIM ANYEPGLHYF AEWWKQLFGE SEGKDGKGIY
     PASVDFTTDL HSMGQYIQDG LRHIFETVLN VEKPRYDIEI MEDKDNIDGL NFLAGKTMDF
     VNKKAFEGTV LAHTDGNVPN IIINIPELTP YYFGKLVYMF EKACGISGYI LGVNPFDQPG
     VEAYKKNMFA LLGKPGFEEQ RRKLEEILGR
//