ID A0A1E8PVY0_9MYCO Unreviewed; 253 AA. AC A0A1E8PVY0; DT 15-FEB-2017, integrated into UniProtKB/TrEMBL. DT 15-FEB-2017, sequence version 1. DT 27-NOV-2024, entry version 30. DE RecName: Full=L,D-TPase catalytic domain-containing protein {ECO:0000259|PROSITE:PS52029}; GN ORFNames=BEL07_28680 {ECO:0000313|EMBL:OFJ50361.1}; OS Mycolicibacterium grossiae. OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; OC Mycolicibacterium. OX NCBI_TaxID=1552759 {ECO:0000313|EMBL:OFJ50361.1, ECO:0000313|Proteomes:UP000178953}; RN [1] {ECO:0000313|EMBL:OFJ50361.1, ECO:0000313|Proteomes:UP000178953} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SCH {ECO:0000313|EMBL:OFJ50361.1, RC ECO:0000313|Proteomes:UP000178953}; RA Greninger A.L., Qin X., Jerome K., Vora S., Quinn K.; RT "genome sequence of Mycobacterium sp. 739 SCH."; RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases. CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis. CC {ECO:0000256|ARBA:ARBA00004752, ECO:0000256|PROSITE-ProRule:PRU01373}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OFJ50361.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MCHX01000140; OFJ50361.1; -; Genomic_DNA. DR RefSeq; WP_070356410.1; NZ_MCHX01000140.1. DR AlphaFoldDB; A0A1E8PVY0; -. DR OrthoDB; 5242354at2; -. DR UniPathway; UPA00219; -. DR Proteomes; UP000178953; Unassembled WGS sequence. DR GO; GO:0005576; C:extracellular region; IEA:TreeGrafter. DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW. DR GO; GO:0071972; F:peptidoglycan L,D-transpeptidase activity; IEA:TreeGrafter. DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-UniRule. DR GO; GO:0018104; P:peptidoglycan-protein cross-linking; IEA:TreeGrafter. DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule. DR CDD; cd13431; LDT_IgD_like_1; 1. DR CDD; cd16913; YkuD_like; 1. DR Gene3D; 2.60.40.3710; -; 1. DR Gene3D; 2.40.440.10; L,D-transpeptidase catalytic domain-like; 1. DR InterPro; IPR041280; Big_10. DR InterPro; IPR050979; LD-transpeptidase. DR InterPro; IPR005490; LD_TPept_cat_dom. DR InterPro; IPR038063; Transpep_catalytic_dom. DR PANTHER; PTHR30582; L,D-TRANSPEPTIDASE; 1. DR PANTHER; PTHR30582:SF35; L,D-TRANSPEPTIDASE 2; 1. DR Pfam; PF17964; Big_10; 1. DR Pfam; PF03734; YkuD; 1. DR SUPFAM; SSF141523; L,D-transpeptidase catalytic domain-like; 1. DR PROSITE; PS52029; LD_TPASE; 1. PE 4: Predicted; KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315}; KW Cell shape {ECO:0000256|ARBA:ARBA00022960, ECO:0000256|PROSITE- KW ProRule:PRU01373}; KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316, KW ECO:0000256|PROSITE-ProRule:PRU01373}; KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984, KW ECO:0000256|PROSITE-ProRule:PRU01373}; KW Reference proteome {ECO:0000313|Proteomes:UP000178953}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT SIGNAL 1..32 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 33..253 FT /note="L,D-TPase catalytic domain-containing protein" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5030026931" FT DOMAIN 127..252 FT /note="L,D-TPase catalytic" FT /evidence="ECO:0000259|PROSITE:PS52029" FT ACT_SITE 210 FT /note="Proton donor/acceptor" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01373" FT ACT_SITE 228 FT /note="Nucleophile" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01373" SQ SEQUENCE 253 AA; 26052 MW; 24EB683931687E89 CRC64; MTLFDTMRRL LAVSGLATLV VAASIGVGSA HAAAPTGQQA VASVSPAAGD VVGVAAPVTV TFAGSVPDRA AAQRSLRFTS GGAPSGRFSW PADDVMQWTP DGFFPAHSTV ALSVGGVKTN FRTGAEVLGV ADIDAHTFTV SIDGVVAREM PASMGKPKFP TPIGTFSALE KQNVVVMDSR TIGIPLSDAE GYKLTVYDAV RVTWGGVYVH GAPWSTGSQG NSNVSHGCIN LSADNAAWYY DQVSVGDPII VRA //