ID A0A1E7Q4V5_9GAMM Unreviewed; 881 AA. AC A0A1E7Q4V5; DT 18-JAN-2017, integrated into UniProtKB/TrEMBL. DT 18-JAN-2017, sequence version 1. DT 27-NOV-2024, entry version 35. DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438}; DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438}; GN ORFNames=BI198_05440 {ECO:0000313|EMBL:OEY69078.1}; OS Rheinheimera salexigens. OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae; OC Rheinheimera. OX NCBI_TaxID=1628148 {ECO:0000313|EMBL:OEY69078.1, ECO:0000313|Proteomes:UP000242258}; RN [1] {ECO:0000313|Proteomes:UP000242258} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KH87 {ECO:0000313|Proteomes:UP000242258}; RA Wan X., Hou S.; RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085}; CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OEY69078.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MKEK01000001; OEY69078.1; -; Genomic_DNA. DR RefSeq; WP_070048644.1; NZ_MKEK01000001.1. DR AlphaFoldDB; A0A1E7Q4V5; -. DR STRING; 1628148.BI198_05440; -. DR OrthoDB; 5563233at2; -. DR Proteomes; UP000242258; Unassembled WGS sequence. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0009927; F:histidine phosphotransfer kinase activity; IEA:TreeGrafter. DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro. DR GO; GO:0046777; P:protein autophosphorylation; IEA:TreeGrafter. DR CDD; cd14686; bZIP; 1. DR CDD; cd06225; HAMP; 1. DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1. DR CDD; cd00082; HisKA; 1. DR CDD; cd00088; HPT; 1. DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1. DR FunFam; 1.10.287.130:FF:000004; Ethylene receptor 1; 1. DR FunFam; 3.30.565.10:FF:000010; Sensor histidine kinase RcsC; 1. DR Gene3D; 1.10.287.130; -; 1. DR Gene3D; 3.40.50.2300; -; 1. DR Gene3D; 6.10.340.10; -; 1. DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1. DR Gene3D; 1.20.120.160; HPT domain; 1. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR003660; HAMP_dom. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR003594; HATPase_dom. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR003661; HisK_dim/P_dom. DR InterPro; IPR036097; HisK_dim/P_sf. DR InterPro; IPR036641; HPT_dom_sf. DR InterPro; IPR029151; Sensor-like_sf. DR InterPro; IPR004358; Sig_transdc_His_kin-like_C. DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1. DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1. DR Pfam; PF00672; HAMP; 1. DR Pfam; PF02518; HATPase_c; 1. DR Pfam; PF00512; HisKA; 1. DR Pfam; PF01627; Hpt; 1. DR Pfam; PF00072; Response_reg; 1. DR PRINTS; PR00344; BCTRLSENSOR. DR SMART; SM00304; HAMP; 1. DR SMART; SM00387; HATPase_c; 1. DR SMART; SM00388; HisKA; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1. DR SUPFAM; SSF52172; CheY-like; 1. DR SUPFAM; SSF158472; HAMP domain-like; 1. DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1. DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1. DR SUPFAM; SSF103190; Sensory domain-like; 1. DR PROSITE; PS50885; HAMP; 1. DR PROSITE; PS50109; HIS_KIN; 1. DR PROSITE; PS50894; HPT; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OEY69078.1}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE- KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000242258}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}. FT TRANSMEM 7..29 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 281..305 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 307..359 FT /note="HAMP" FT /evidence="ECO:0000259|PROSITE:PS50885" FT DOMAIN 413..631 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" FT DOMAIN 662..776 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT DOMAIN 792..881 FT /note="HPt" FT /evidence="ECO:0000259|PROSITE:PS50894" FT COILED 365..406 FT /evidence="ECO:0000256|SAM:Coils" FT MOD_RES 711 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" FT MOD_RES 831 FT /note="Phosphohistidine" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110" SQ SEQUENCE 881 AA; 99704 MW; 8184D5AC8F66CE4F CRC64; MRLRQTLVVY MLPLLLLPVI GFGYLAYYFQ QQQIDKQTLF QAQQALNKQA DHLDRFFQHY LVQLGMLAQS ASLHQYLSQP TATNQSYLSS RLQDFANADR SISSVKVLHL NGDYAVQVPQ QPDVSNIPNR FRNRYFSSLQ AQVDEAGFFL ARENTNQQLQ LYFAQKIYSV SVTDSRQLWG YLVVVVEPSR LQQEINYQHT PNSRTLLINK SATIIYAANT ANIGSVIAPA DFRRIQSSIE QQQFERATLF AQPRVVLGQN LTANYQLLLS LDETDLYPAP LLSWLIIGLI LIVCIMIPLC VYFLLIRNVL APIRQLTAAK TAVGRGDFSI LLEVNKHDEL GDMFAAFNVM VRQLRVYRER ERAYKQQLED KVLRRTQDLE RANDDLAAVN QELILARETA EQANKLKSVF LANMSHEIRT PLTAIIGFSE QAVQENEGIK RENYLQRVLK SSEHLLSLIN DILDLSKIEA EKLELAPEYF NCLALIDDVY QQTQAQADAI GLQCRLEWQY PLPQIIYNDA LRFRQVLLNL TSNAIKFTTK GKVIIHVSFD VVSQQLIIKV KDTGIGMTAV ELSRIFKPFV QADATVTRHF GGSGLGLCIS KKLMQQMDGD IFVDSVKGIG SCFEMRFNCQ QQTLDLIDQY HRDLKVSVPA IVEVDPNMHK LHILVAEDNQ DNQLLLSLML DKAHATYVIV ENGHLAVERA LAESFDIIFM DMQMPVMGGE EATRLIRYAG IDTAIIAVTA NIMTDDIEHY KQSGCQAVLA KPIILAELTA ILSRYGERSD RAMLSLDLQL EQDPQMKALK QHFTAQLPIL FAEFEQLFAA QTWDKLSFAA HSLKGSAGSM GYPELTAFSD KLELAAQQQH SAEVAALLEQ MQLIIEKAQQ D //