ID   A0A1E7Q4V5_9GAMM        Unreviewed;       881 AA.
AC   A0A1E7Q4V5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   12-AUG-2020, entry version 23.
DE   RecName: Full=Histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=BI198_05440 {ECO:0000313|EMBL:OEY69078.1};
OS   Rheinheimera salexigens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Rheinheimera.
OX   NCBI_TaxID=1628148 {ECO:0000313|EMBL:OEY69078.1, ECO:0000313|Proteomes:UP000242258};
RN   [1] {ECO:0000313|Proteomes:UP000242258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH87 {ECO:0000313|Proteomes:UP000242258};
RA   Wan X., Hou S.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEY69078.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MKEK01000001; OEY69078.1; -; Genomic_DNA.
DR   RefSeq; WP_070048644.1; NZ_MKEK01000001.1.
DR   BioCyc; GCF_001752395:BI198_RS05435-MONOMER; -.
DR   Proteomes; UP000242258; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00088; HPT; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 1.20.120.160; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR036641; HPT_dom_sf.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF01627; Hpt; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF103190; SSF103190; 1.
DR   SUPFAM; SSF47226; SSF47226; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50894; HPT; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OEY69078.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW   ProRule:PRU00110}; Reference proteome {ECO:0000313|Proteomes:UP000242258};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          307..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          413..631
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   DOMAIN          662..776
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          792..881
FT                   /note="HPt"
FT                   /evidence="ECO:0000259|PROSITE:PS50894"
FT   COILED          365..406
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   MOD_RES         711
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT   MOD_RES         831
FT                   /note="Phosphohistidine"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ   SEQUENCE   881 AA;  99704 MW;  8184D5AC8F66CE4F CRC64;
     MRLRQTLVVY MLPLLLLPVI GFGYLAYYFQ QQQIDKQTLF QAQQALNKQA DHLDRFFQHY
     LVQLGMLAQS ASLHQYLSQP TATNQSYLSS RLQDFANADR SISSVKVLHL NGDYAVQVPQ
     QPDVSNIPNR FRNRYFSSLQ AQVDEAGFFL ARENTNQQLQ LYFAQKIYSV SVTDSRQLWG
     YLVVVVEPSR LQQEINYQHT PNSRTLLINK SATIIYAANT ANIGSVIAPA DFRRIQSSIE
     QQQFERATLF AQPRVVLGQN LTANYQLLLS LDETDLYPAP LLSWLIIGLI LIVCIMIPLC
     VYFLLIRNVL APIRQLTAAK TAVGRGDFSI LLEVNKHDEL GDMFAAFNVM VRQLRVYRER
     ERAYKQQLED KVLRRTQDLE RANDDLAAVN QELILARETA EQANKLKSVF LANMSHEIRT
     PLTAIIGFSE QAVQENEGIK RENYLQRVLK SSEHLLSLIN DILDLSKIEA EKLELAPEYF
     NCLALIDDVY QQTQAQADAI GLQCRLEWQY PLPQIIYNDA LRFRQVLLNL TSNAIKFTTK
     GKVIIHVSFD VVSQQLIIKV KDTGIGMTAV ELSRIFKPFV QADATVTRHF GGSGLGLCIS
     KKLMQQMDGD IFVDSVKGIG SCFEMRFNCQ QQTLDLIDQY HRDLKVSVPA IVEVDPNMHK
     LHILVAEDNQ DNQLLLSLML DKAHATYVIV ENGHLAVERA LAESFDIIFM DMQMPVMGGE
     EATRLIRYAG IDTAIIAVTA NIMTDDIEHY KQSGCQAVLA KPIILAELTA ILSRYGERSD
     RAMLSLDLQL EQDPQMKALK QHFTAQLPIL FAEFEQLFAA QTWDKLSFAA HSLKGSAGSM
     GYPELTAFSD KLELAAQQQH SAEVAALLEQ MQLIIEKAQQ D
//