ID A0A1E4LMI1_9BURK Unreviewed; 618 AA. AC A0A1E4LMI1; DT 18-JAN-2017, integrated into UniProtKB/TrEMBL. DT 18-JAN-2017, sequence version 1. DT 29-SEP-2021, entry version 19. DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551}; DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551}; GN ORFNames=ABT02_17130 {ECO:0000313|EMBL:ODU57532.1}; OS Comamonadaceae bacterium SCN 68-20. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Comamonadaceae. OX NCBI_TaxID=1660161 {ECO:0000313|EMBL:ODU57532.1, ECO:0000313|Proteomes:UP000095151}; RN [1] {ECO:0000313|EMBL:ODU57532.1, ECO:0000313|Proteomes:UP000095151} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=26031303; DOI=10.1111/1462-2920.12936; RA Kantor R.S., van Zyl A.W., van Hille R.P., Thomas B.C., Harrison S.T., RA Banfield J.F.; RT "Bioreactor microbial ecosystems for thiocyanate and cyanide degradation RT unravelled with genome-resolved metagenomics."; RL Environ. Microbiol. 17:4929-4941(2015). CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12; CC Evidence={ECO:0000256|ARBA:ARBA00001665}; CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily. CC {ECO:0000256|ARBA:ARBA00005446}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:ODU57532.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MEFU01000056; ODU57532.1; -; Genomic_DNA. DR EnsemblBacteria; ODU57532; ODU57532; ABT02_17130. DR Proteomes; UP000095151; Unassembled WGS sequence. DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0140603; F:ATP hydrolysis activity; IEA:RHEA. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0006310; P:DNA recombination; IEA:InterPro. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR GO; GO:0006260; P:DNA replication; IEA:InterPro. DR GO; GO:0009432; P:SOS response; IEA:InterPro. DR Gene3D; 1.10.10.10; -; 1. DR Gene3D; 3.40.50.300; -; 2. DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom. DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ. DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac. DR InterPro; IPR014001; Helicase_ATP-bd. DR InterPro; IPR001650; Helicase_C. DR InterPro; IPR010997; HRDC-like_sf. DR InterPro; IPR002121; HRDC_dom. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR032284; RecQ_Zn-bd. DR InterPro; IPR018982; RQC_domain. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR Pfam; PF00270; DEAD; 1. DR Pfam; PF00271; Helicase_C; 1. DR Pfam; PF00570; HRDC; 1. DR Pfam; PF16124; RecQ_Zn_bind; 1. DR Pfam; PF09382; RQC; 1. DR SMART; SM00487; DEXDc; 1. DR SMART; SM00490; HELICc; 1. DR SMART; SM00341; HRDC; 1. DR SMART; SM00956; RQC; 1. DR SUPFAM; SSF47819; SSF47819; 1. DR SUPFAM; SSF52540; SSF52540; 2. DR TIGRFAMs; TIGR01389; recQ; 1. DR TIGRFAMs; TIGR00614; recQ_fam; 1. DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1. DR PROSITE; PS51194; HELICASE_CTER; 1. DR PROSITE; PS50967; HRDC; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ODU57532.1}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}. FT DOMAIN 25..201 FT /note="Helicase ATP-binding" FT /evidence="ECO:0000259|PROSITE:PS51192" FT DOMAIN 222..373 FT /note="Helicase C-terminal" FT /evidence="ECO:0000259|PROSITE:PS51194" FT DOMAIN 546..618 FT /note="HRDC" FT /evidence="ECO:0000259|PROSITE:PS50967" SQ SEQUENCE 618 AA; 67676 MW; 9AD28DBCF7696A7C CRC64; MSPAHSVLHD VFGYAQFRGP QEAIVEHVIA GGDALVLMPT GGGKSLCYQV PAIVRRDAGR GVTVVVSPLI ALMHDQVGAL HEAGVDAAFL NSTLDWQQTL DVERRLARGE ITLLYAAPER VTTERFLGLL DDLHARGQLG LFAIDEAHCV SQWGHDFRPE YRQLSILHER YPGVPRVALT ATADELTRAD IVEGLRLQGA RLFLSSFDRP NIRYRIEEKK EPLAQLLRFI EREHLGDAGV VYCQSRKRVE EMAEALAQAG IDALPYHAGL PADTRQAHQD RFLREDGVVV VATIAFGMGI DKPDVRFVAH VDMPKNIEGY YQETGRAGRD GLPADAWMVY GLQDVVNQRR MIDDGEAGEE FKAVMRAKLD ALLALAEATD CRRQRLLSYF GETSKPCGNC DNCIAPPAVW DGTDAARKLL STIYRVHEAS GLTFGVGHLM DIVRGKLTDK VRQFGHDKLS TFNLGAQYSE AQLRGVLRQL LAVGAVGVHR VAMENGHSFD TLTLSHGSRP VLRGEQTVML REASAHAAPK KARRAAAPPV AAANLGADAQ VRFINLKAWR AEVARAHNLP AYVIFHDATL AAIAERNPAT LEDLQGISGM GAKKLEAYGA EVLRVVQG //