ID A0A1C9ZVX7_HORVS Unreviewed; 488 AA. AC A0A1C9ZVX7; DT 30-NOV-2016, integrated into UniProtKB/TrEMBL. DT 30-NOV-2016, sequence version 1. DT 27-MAR-2024, entry version 20. DE SubName: Full=NADH dehydrogenase subunit 2 {ECO:0000313|EMBL:BAV58097.1}; GN Name=nad2 {ECO:0000313|EMBL:BAV58097.1}; OS Hordeum vulgare subsp. spontaneum (Wild barley) (Hordeum spontaneum). OG Mitochondrion {ECO:0000313|EMBL:BAV58097.1}. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum. OX NCBI_TaxID=77009 {ECO:0000313|EMBL:BAV58097.1}; RN [1] {ECO:0000313|EMBL:BAV58097.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=H602 {ECO:0000313|EMBL:BAV58097.1}; RC TISSUE=Etiolated seedling {ECO:0000313|EMBL:BAV58097.1}; RX PubMed=27776481; DOI=10.1186/s12864-016-3159-3; RA Hisano H., Tsujimura M., Yoshida H., Terachi T., Sato K.; RT "Mitochondrial genome sequences from wild and cultivated barley (Hordeum RT vulgare)."; RL BMC Genomics 17:824-824(2016). RN [2] {ECO:0000313|EMBL:QGK86004.1} RP NUCLEOTIDE SEQUENCE. RA Makarevich A., Pankratov V., Siniauskaya M., Liaudanski A.; RT "Organelle genomes phylogeny of wild and cultivated barley forms."; RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain CC NADH dehydrogenase (Complex I) that is believed to belong to the CC minimal assembly required for catalysis. Complex I functions in the CC transfer of electrons from NADH to the respiratory chain. The immediate CC electron acceptor for the enzyme is believed to be ubiquinone. CC {ECO:0000256|ARBA:ARBA00003257}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP017300; BAV58097.1; -; Genomic_DNA. DR EMBL; MN127970; QGK86004.1; -; Genomic_DNA. DR EMBL; MN127971; QGK86042.1; -; Genomic_DNA. DR EMBL; MN127972; QGK86080.1; -; Genomic_DNA. DR EMBL; MN127973; QGK86118.1; -; Genomic_DNA. DR EMBL; MN127974; QGK86156.1; -; Genomic_DNA. DR EMBL; MN127977; QGK86270.1; -; Genomic_DNA. DR EMBL; MN127978; QGK86308.1; -; Genomic_DNA. DR EMBL; MN127980; QGK86384.1; -; Genomic_DNA. DR EMBL; MN127981; QGK86422.1; -; Genomic_DNA. DR EMBL; MN127982; QGK86460.1; -; Genomic_DNA. DR AlphaFoldDB; A0A1C9ZVX7; -. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW. DR GO; GO:0009536; C:plastid; IEA:UniProt. DR GO; GO:0009579; C:thylakoid; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro. DR HAMAP; MF_00445; NDH1_NuoN_1; 1. DR InterPro; IPR010096; NADH-Q_OxRdtase_suN/2. DR InterPro; IPR001750; ND/Mrp_mem. DR NCBIfam; TIGR01770; NDH_I_N; 1. DR PANTHER; PTHR22773; NADH DEHYDROGENASE; 1. DR PANTHER; PTHR22773:SF113; NADH DEHYDROGENASE SUBUNIT 2-RELATED; 1. DR Pfam; PF00361; Proton_antipo_M; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000313|EMBL:BAV58097.1}; KW NAD {ECO:0000256|ARBA:ARBA00023027}; KW Thylakoid {ECO:0000256|ARBA:ARBA00023078}; KW Translocase {ECO:0000256|ARBA:ARBA00022967}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 12..31 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 43..69 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 81..104 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 135..154 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 166..187 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 207..228 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 282..300 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 334..355 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 375..394 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 400..429 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 131..425 FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane FT subunit" FT /evidence="ECO:0000259|Pfam:PF00361" SQ SEQUENCE 488 AA; 53643 MW; B14F9B1BDE3CA87C CRC64; MFNLFLAVSP EIFIINATFI LLIHGVVFST SKKDDYPPLV SNVGWLGLLS VLITLLLLAA GAPLLTIAHL FWNNFFRRDN FTYFCQILLL LSTAGTISMC FDFFEKERFD ASEFIVLIPL PTRSMLLMIP AHDLIAMYLA IELQSLCFYV IAASKRKSEF STEAGSKYLI LGAFPSGILL FGCSMIYGST GATHFDQLAK ILTGYEITGA RSSGIFMGIL FIAVGSLFKI TAVPFHMWAP DIYEGSPTPV TAFLSIAPKI SISANMSRVS IVASYGGTLQ QIFFFCSIAS MILGALAAMA QTKVKRPLAH SSIGHVGYIR TGFSCGTIEG IQSLLIGIFI YASMTIDAFA IVPALRQTRV KYIADLGALA KTNPISAMTF SITMFSYAGI PPLAGFCSKF YLFFAALGCG AYFLAPVGVV TSVIGRFYYI RLAKRMFFDR PRTWILYEPM DRDKSLLLAM TSSFITSSFP YPSPLFDLTH QMALSSYL //