ID   A0A1C9TBB7_STRSA        Unreviewed;       143 AA.
AC   A0A1C9TBB7;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE            EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE   Flags: Fragment;
GN   Name=gyrB {ECO:0000313|EMBL:AOR07873.1};
OS   Streptococcus sanguinis.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1305 {ECO:0000313|EMBL:AOR07873.1};
RN   [1] {ECO:0000313|EMBL:AOR07873.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PUA044 {ECO:0000313|EMBL:AOR07842.1}, PUA072
RC   {ECO:0000313|EMBL:AOR07870.1}, PUA073 {ECO:0000313|EMBL:AOR07871.1},
RC   PUA074 {ECO:0000313|EMBL:AOR07872.1}, PUA075
RC   {ECO:0000313|EMBL:AOR07873.1}, PUA076 {ECO:0000313|EMBL:AOR07874.1},
RC   and PUA083 {ECO:0000313|EMBL:AOR07881.1};
RX   PubMed=27617008; DOI=10.3389/fmicb.2016.01328;
RA   Zhou M., Yang Q., Kudinha T., Zhang L., Xiao M., Kong F., Zhao Y., Xu Y.C.;
RT   "Using Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-
RT   TOF) Complemented with Selected 16S rRNA and gyrB Genes Sequencing to
RT   Practically Identify Clinical Important Viridans Group Streptococci
RT   (VGS).";
RL   Front. Microbiol. 7:1328-1328(2016).
RN   [2] {ECO:0000313|EMBL:AOR07873.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PUA044 {ECO:0000313|EMBL:AOR07842.1}, PUA072
RC   {ECO:0000313|EMBL:AOR07870.1}, PUA073 {ECO:0000313|EMBL:AOR07871.1},
RC   PUA074 {ECO:0000313|EMBL:AOR07872.1}, PUA075
RC   {ECO:0000313|EMBL:AOR07873.1}, PUA076 {ECO:0000313|EMBL:AOR07874.1},
RC   and PUA083 {ECO:0000313|EMBL:AOR07881.1};
RA   Seilhamer J.J.;
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-dependent breakage, passage and rejoining of double-
CC         stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
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DR   EMBL; KX661267; AOR07842.1; -; Genomic_DNA.
DR   EMBL; KX661295; AOR07870.1; -; Genomic_DNA.
DR   EMBL; KX661296; AOR07871.1; -; Genomic_DNA.
DR   EMBL; KX661297; AOR07872.1; -; Genomic_DNA.
DR   EMBL; KX661298; AOR07873.1; -; Genomic_DNA.
DR   EMBL; KX661299; AOR07874.1; -; Genomic_DNA.
DR   EMBL; KX661306; AOR07881.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C9TBB7; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.670; -; 1.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   InterPro; IPR001241; Topo_IIA.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR000565; Topo_IIA_B.
DR   InterPro; IPR013759; Topo_IIA_B_C.
DR   InterPro; IPR018522; TopoIIA_CS.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR01159; DNAGYRASEB.
DR   PRINTS; PR00418; TPI2FAMILY.
DR   SMART; SM00433; TOP2c; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR   PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT   DOMAIN          65..143
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AOR07873.1"
FT   NON_TER         143
FT                   /evidence="ECO:0000313|EMBL:AOR07873.1"
SQ   SEQUENCE   143 AA;  15519 MW;  256360147D0151B1 CRC64;
     SEAFSDFLLE NPAVARKIVE KGILASKARI AAKRAREVTR KKSGLEISNL PGKLADCSSN
     DPQETELFIV EGDSAGGSAK SGRNREFQAI LPIRGKILNV EKASMDKILA NEEIRSLFTA
     MGTGFGADFD VSKARYQKLV IMT
//