ID A0A1C9HJI0_WHEAT Unreviewed; 443 AA. AC A0A1C9HJI0; DT 30-NOV-2016, integrated into UniProtKB/TrEMBL. DT 30-NOV-2016, sequence version 1. DT 24-JUL-2024, entry version 27. DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}; DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}; GN Name=CIPK9 {ECO:0000313|EMBL:AOO86830.1}; OS Triticum aestivum (Wheat). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum. OX NCBI_TaxID=4565 {ECO:0000313|EMBL:AOO86830.1}; RN [1] {ECO:0000313|EMBL:AOO86830.1} RP NUCLEOTIDE SEQUENCE. RA Guo J., Liu P., Duan Y., Kang Z.; RT "Crosstalk between the wheat CBL-CIPK and SA signaling pathways in the RT wheat-Puccinia striiformis f. sp. tritici pathosystem."; RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; CC Evidence={ECO:0000256|ARBA:ARBA00001433}; CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775}; CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr CC protein kinase family. SNF1 subfamily. {ECO:0000256|ARBA:ARBA00006234}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KU736855; AOO86830.1; -; mRNA. DR AlphaFoldDB; A0A1C9HJI0; -. DR ExpressionAtlas; A0A1C9HJI0; baseline and differential. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR CDD; cd12195; CIPK_C; 1. DR Gene3D; 3.30.310.80; Kinase associated domain 1, KA1; 1. DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR018451; NAF/FISL_domain. DR InterPro; IPR004041; NAF_dom. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR PANTHER; PTHR43895; CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED; 1. DR PANTHER; PTHR43895:SF145; CBL-INTERACTING SERINE_THREONINE-PROTEIN KINASE 9; 1. DR Pfam; PF03822; NAF; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1. DR PROSITE; PS50816; NAF; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 2: Evidence at transcript level; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE- KW ProRule:PRU10141}; KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AOO86830.1}; KW Manganese {ECO:0000256|ARBA:ARBA00023211}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE- KW ProRule:PRU10141}; KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 17..272 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT DOMAIN 309..333 FT /note="NAF" FT /evidence="ECO:0000259|PROSITE:PS50816" FT BINDING 46 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141" SQ SEQUENCE 443 AA; 49768 MW; DDBDF3B18066DC9D CRC64; MAAAGGGPRR TTRVGPYELG KTVGEGSFAK VKIAKDTRNA ATCAIKVLDR NHVLRHKMVE QIKREIATMK LIRHPNVVQL HEVMASKSKI YMVLEFVEGG ELFDKIVNSG KLGEDEARRY FHQLINAVDY CHSRGVYHRD LKPENLLLDS YGALKVSDFG LSAFSPQTKE DGLLHTACGT PNYVAPEVLA DKGYDGMAAD VWSCGIILFV LMAGYLPFDD PNLMTLYKLI ARANVSCPPW FSTGARNLIK RILDPNPHTR ITIAQILEDE WFKKDYKPPQ SEHNEDVSLE DVDAAFDSSE EHLVAERREK PESMNAFALI SRSEGFNLGN LFEKEMMGMV KRETSFASQR TPQEIMSKIE EACGPLGFNV RKQNYKMKLK GDKTGRKGHL SVATEVFEVA PTLHMVELRK TGGDALEFHS FYKNFSSELK DIVWKTESNT IAK //