ID A0A1C7CCT6_PSEAI Unreviewed; 72 AA. AC A0A1C7CCT6; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 30-NOV-2016, entry version 2. DE RecName: Full=Translation initiation factor IF-1 {ECO:0000256|HAMAP-Rule:MF_00075}; GN Name=infA {ECO:0000256|HAMAP-Rule:MF_00075}; GN ORFNames=Q058_02013 {ECO:0000313|EMBL:ERV82923.1}; OS Pseudomonas aeruginosa BL04. OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. OX NCBI_TaxID=1402545 {ECO:0000313|EMBL:ERV82923.1, ECO:0000313|Proteomes:UP000017518}; RN [1] {ECO:0000313|EMBL:ERV82923.1, ECO:0000313|Proteomes:UP000017518} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BL04 {ECO:0000313|EMBL:ERV82923.1, RC ECO:0000313|Proteomes:UP000017518}; RG The Broad Institute Genomics Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Hung D., Penaranda C., Poulsen B., Young S.K., Zeng Q., Gargeya S., RA Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B., RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., RA Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., RA Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.; RT "The Genome Sequence of Pseudomonas aeruginosa BL04."; RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: One of the essential components for the initiation of CC protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the CC 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently CC binds. Helps modulate mRNA selection, yielding the 30S pre- CC initiation complex (PIC). Upon addition of the 50S ribosomal CC subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S CC translation initation complex. {ECO:0000256|HAMAP-Rule:MF_00075, CC ECO:0000256|SAAS:SAAS00571771}. CC -!- SUBUNIT: Component of the 30S ribosomal translation pre-initiation CC complex which assembles on the 30S ribosome in the order IF-2 and CC IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can CC occur at any time during PIC assembly. {ECO:0000256|HAMAP- CC Rule:MF_00075, ECO:0000256|SAAS:SAAS00326798}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075, CC ECO:0000256|SAAS:SAAS00571807}. CC -!- SIMILARITY: Belongs to the IF-1 family. {ECO:0000256|HAMAP- CC Rule:MF_00075, ECO:0000256|SAAS:SAAS00571750}. CC -!- SIMILARITY: Contains 1 S1-like domain. {ECO:0000256|HAMAP- CC Rule:MF_00075, ECO:0000256|RuleBase:RU004366}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:ERV82923.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AXPW01000001; ERV82923.1; -; Genomic_DNA. DR RefSeq; WP_002553999.1; NZ_KI518931.1. DR GeneID; 7821956; -. DR Proteomes; UP000017518; Unassembled WGS sequence. DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. DR CDD; cd04451; S1_IF1; 1. DR HAMAP; MF_00075; IF_1; 1. DR InterPro; IPR012340; NA-bd_OB-fold. DR InterPro; IPR006196; RNA-binding_domain_S1_IF1. DR InterPro; IPR022967; S1_dom. DR InterPro; IPR004368; TIF_IF1. DR Pfam; PF01176; eIF-1a; 1. DR SMART; SM00316; S1; 1. DR SUPFAM; SSF50249; SSF50249; 1. DR TIGRFAMs; TIGR00008; infA; 1. DR PROSITE; PS50832; S1_IF1_TYPE; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000017518}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075, KW ECO:0000256|SAAS:SAAS00571747}; KW Initiation factor {ECO:0000256|HAMAP-Rule:MF_00075, KW ECO:0000256|SAAS:SAAS00462727, ECO:0000313|EMBL:ERV82923.1}; KW Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00075, KW ECO:0000256|SAAS:SAAS00462770}; KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_00075, KW ECO:0000256|SAAS:SAAS00571734}; KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00075, KW ECO:0000256|SAAS:SAAS00571792}. SQ SEQUENCE 72 AA; 8303 MW; 97E5EEFD8F3886DB CRC64; MSKEDSFEME GTVVDTLPNT MFRVELENGH VVTAHISGKM RKNYIRILTG DKVRVELTPY DLSKGRITYR AR //