ID A0A1C7BJQ4_PSEAI Unreviewed; 195 AA. AC A0A1C7BJQ4; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 11-DEC-2019, entry version 10. DE RecName: Full=2-hydroxychromene-2-carboxylate isomerase {ECO:0000256|PIRNR:PIRNR006386}; DE EC=5.99.1.4 {ECO:0000256|PIRNR:PIRNR006386}; GN ORFNames=Q058_04681 {ECO:0000313|EMBL:ERV74105.1}; OS Pseudomonas aeruginosa BL04. OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. OX NCBI_TaxID=1402545 {ECO:0000313|EMBL:ERV74105.1, ECO:0000313|Proteomes:UP000017518}; RN [1] {ECO:0000313|EMBL:ERV74105.1, ECO:0000313|Proteomes:UP000017518} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BL04 {ECO:0000313|EMBL:ERV74105.1, RC ECO:0000313|Proteomes:UP000017518}; RG The Broad Institute Genomics Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Hung D., Penaranda C., Poulsen B., Young S.K., Zeng Q., Gargeya S., RA Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B., Gainer-Dewar J., RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., RA Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., RA Birren B.; RT "The Genome Sequence of Pseudomonas aeruginosa BL04."; RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2- CC oxobut-3-enoate; Xref=Rhea:RHEA:27401, ChEBI:CHEBI:59350, CC ChEBI:CHEBI:59353; EC=5.99.1.4; CC Evidence={ECO:0000256|PIRNR:PIRNR006386}; CC -!- SIMILARITY: Belongs to the GST superfamily. NadH family. CC {ECO:0000256|PIRNR:PIRNR006386}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:ERV74105.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AXPW01000012; ERV74105.1; -; Genomic_DNA. DR RefSeq; WP_023107523.1; NZ_KI518936.1. DR EnsemblBacteria; ERV74105; ERV74105; Q058_04681. DR PATRIC; fig|1402545.3.peg.4679; -. DR Proteomes; UP000017518; Unassembled WGS sequence. DR GO; GO:0018845; F:2-hydroxychromene-2-carboxylate isomerase activity; IEA:UniProtKB-UniRule. DR GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro. DR Gene3D; 3.40.30.10; -; 1. DR InterPro; IPR001853; DSBA-like_thioredoxin_dom. DR InterPro; IPR014440; HCCAis_GSTk. DR InterPro; IPR036249; Thioredoxin-like_sf. DR Pfam; PF01323; DSBA; 1. DR PIRSF; PIRSF006386; HCCAis_GSTk; 1. DR SUPFAM; SSF52833; SSF52833; 1. PE 3: Inferred from homology; KW Isomerase {ECO:0000256|PIRNR:PIRNR006386}. FT DOMAIN 4..194 FT /note="DSBA" FT /evidence="ECO:0000259|Pfam:PF01323" FT ACT_SITE 13 FT /note="Nucleophile" FT /evidence="ECO:0000256|PIRSR:PIRSR006386-1" SQ SEQUENCE 195 AA; 21432 MW; B92B028D80BEB64F CRC64; MSKQIEFFFD FGSPSTYLAW TQLPRIAAAH GASIAWRPML LGGVFKATGN HSPIEVPAKG RYTLHDLARY AKRYGVPLAF NPAFPINTLT LMRGAQGYLG GEGFQPYLKA VFEALWVRQQ NLGKPEVVAQ VLAEAGFDPD EFLRLVGDEQ VKEGLKATTE EAVRRGVFGA PSFFVGDQLF FGQDRLDFVA EALAG //