ID A0A1B9HEJ4_9TREE Unreviewed; 970 AA. AC A0A1B9HEJ4; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 14-DEC-2022, entry version 18. DE RecName: Full=HTH La-type RNA-binding domain-containing protein {ECO:0000259|PROSITE:PS50961}; GN ORFNames=I317_04469 {ECO:0000313|EMBL:OCF41663.1}; OS Kwoniella heveanensis CBS 569. OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; OC Tremellales; Cryptococcaceae; Kwoniella. OX NCBI_TaxID=1296119 {ECO:0000313|EMBL:OCF41663.1, ECO:0000313|Proteomes:UP000092564}; RN [1] {ECO:0000313|EMBL:OCF41663.1, ECO:0000313|Proteomes:UP000092564} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 569 {ECO:0000313|EMBL:OCF41663.1, RC ECO:0000313|Proteomes:UP000092564}; RG The Broad Institute Genome Sequencing Platform; RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D., RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S., RA Wortman J., Nusbaum C., Birren B.; RT "The Genome Sequence of Cryptococcus heveanensis CBS569."; RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000092564} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 569 {ECO:0000313|Proteomes:UP000092564}; RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D., RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.; RT "Evolution of pathogenesis and genome organization in the Tremellales."; RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KV700205; OCF41663.1; -; Genomic_DNA. DR AlphaFoldDB; A0A1B9HEJ4; -. DR VEuPathDB; FungiDB:I317_04469; -. DR OrthoDB; 1119460at2759; -. DR Proteomes; UP000092564; Unassembled WGS sequence. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.10.10; -; 1. DR InterPro; IPR045180; La_dom_prot. DR InterPro; IPR006630; La_HTH. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR PANTHER; PTHR22792; LUPUS LA PROTEIN-RELATED; 1. DR Pfam; PF05383; La; 1. DR SMART; SM00715; LA; 1. DR SUPFAM; SSF46785; Winged helix DNA-binding domain; 1. DR PROSITE; PS50961; HTH_LA; 1. PE 4: Predicted; KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE- KW ProRule:PRU00332}. FT DOMAIN 737..827 FT /note="HTH La-type RNA-binding" FT /evidence="ECO:0000259|PROSITE:PS50961" FT REGION 24..220 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 233..680 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 828..850 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 908..970 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 33..70 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 80..106 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 107..124 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 142..180 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 233..297 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 355..393 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 434..453 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 484..504 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 539..553 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 566..632 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 836..850 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 908..922 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 936..954 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 956..970 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 970 AA; 101218 MW; 5817DFAED145C7DB CRC64; MSGTQQAANG NTLSAFNALG SYAGKIKDTD GNFIKPSPSN SNSSPAPMSN GNNNLESASS SSTIPTSTMT KLREPRPAAG TSTKNAQSQQ TAQQSEDDGP WETVQSARQR NRHEEKDRHS HRQSQGHGHG QGHGHGHGQG SNSKNWRDRS HRDGQGQKEK ERQGDEQEKE SKERKSGGGK SSKKGGNSQA PLASAPPAVA EKPARPTAVP TGPTKPAWGA LTQPVKPVAV FTSAASASTP SQVAKEASQP QEITVPPSPS LNGTTMTANS VSVPASIGSP NLSSDTASTS TASASVLSKA VDKLEETGSW RAQPRAETDT AEVPAPVQPA QPRQAAPPPA VNAWDLRKKK MAPANATPNP TSQGKLGASV SQNGGSNAKA ESSQKSVTNG PLKEENAKTP AKKKSPARSA ASTVAPPTLN DATLWPDVAQ AAEVAKATEE KKEKAKEKAE GTSVVEDSAG TGKKPKWTPI PAAELLAAAD HAAEQNRRQS RLEASAKKRL TTPKGEVESS AAGAKGGKPR KGGPPTVPAI ESKKANSHAR PGPTESVNES KASDVTPHAK AGVVNGESST PLSRQISRQS KNGSPSRSQP QLPASTSDST HMRFGSGPLQ SRPMTGSNTA PLPQQGFQPG SSATLPRARG RDGRGSFNGR GRGGFRSNSA MPHKGQGYGS PPLTHSGLPA DGAGFVNGSQ YQRGFMGFQP FYPVGYGPQG IYDPSQAQYG VVYRAGLPPP PMPHTVVPNL DAMRFYVLGQ IEYYFSMQNL AMDFFLRQQM DSEGWIDISM IASFNRLKSL TPDVSIIREC MALSSLLEVR EDQVRLAGLD ANRWVLPDAK PSKFGPDPTS PSQATEESRD ISLGIPASVE QSLSLASHED GQAVQVPPPT QRSLVAADVE NALMKSSAQT AMVTANPITS DAPSSASAAT SIVNGEGAEK AETDIGTATG TGTEAATPAT STSGDAEIKE DAEETEAVKV //