ID A0A1B9ARL2_9BACI Unreviewed; 333 AA. AC A0A1B9ARL2; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 03-JUL-2019, entry version 12. DE RecName: Full=Holliday junction ATP-dependent DNA helicase RuvB {ECO:0000256|HAMAP-Rule:MF_00016}; DE EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_00016}; GN Name=ruvB {ECO:0000256|HAMAP-Rule:MF_00016}; GN ORFNames=A8L44_08985 {ECO:0000313|EMBL:OCA86524.1}; OS Bacillus sp. FJAT-27986. OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. OX NCBI_TaxID=1743146 {ECO:0000313|EMBL:OCA86524.1, ECO:0000313|Proteomes:UP000092673}; RN [1] {ECO:0000313|EMBL:OCA86524.1, ECO:0000313|Proteomes:UP000092673} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FJAT-27986 {ECO:0000313|EMBL:OCA86524.1, RC ECO:0000313|Proteomes:UP000092673}; RA Liu X., Pan Z., Shi H., Ge C., Che J., Lan J., Chen Q., Zhu Y., RA Wang J., Liu B., Liu G.; RT "Bacillus sp. FJAT-27986."; RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: The RuvA-RuvB complex in the presence of ATP renatures CC cruciform structure in supercoiled DNA with palindromic sequence, CC indicating that it may promote strand exchange reactions in CC homologous recombination. RuvAB is a helicase that mediates the CC Holliday junction migration by localized denaturation and CC reannealing. {ECO:0000256|HAMAP-Rule:MF_00016}. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12; CC Evidence={ECO:0000256|HAMAP-Rule:MF_00016}; CC -!- SUBUNIT: Forms a complex with RuvA. {ECO:0000256|HAMAP- CC Rule:MF_00016}. CC -!- SIMILARITY: Belongs to the RuvB family. {ECO:0000256|HAMAP- CC Rule:MF_00016}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:OCA86524.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MAYV01000014; OCA86524.1; -; Genomic_DNA. DR RefSeq; WP_066105481.1; NZ_MAYV01000014.1. DR EnsemblBacteria; OCA86524; OCA86524; A8L44_08985. DR Proteomes; UP000092673; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0009378; F:four-way junction helicase activity; IEA:UniProtKB-UniRule. DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule. DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.10.10; -; 1. DR HAMAP; MF_00016; DNA_helic_RuvB; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR041445; AAA_lid_4. DR InterPro; IPR004605; DNA_helicase_Holl-junc_RuvB. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR008824; RuvB-like_N. DR InterPro; IPR008823; RuvB_C. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR PANTHER; PTHR42848; PTHR42848; 1. DR Pfam; PF17864; AAA_lid_4; 1. DR Pfam; PF05491; RuvB_C; 1. DR Pfam; PF05496; RuvB_N; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF46785; SSF46785; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00635; ruvB; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00016}; KW Complete proteome {ECO:0000313|Proteomes:UP000092673}; KW DNA damage {ECO:0000256|HAMAP-Rule:MF_00016}; KW DNA recombination {ECO:0000256|HAMAP-Rule:MF_00016}; KW DNA repair {ECO:0000256|HAMAP-Rule:MF_00016}; KW Helicase {ECO:0000256|HAMAP-Rule:MF_00016, KW ECO:0000313|EMBL:OCA86524.1}; KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_00016}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00016}; KW Reference proteome {ECO:0000313|Proteomes:UP000092673}; KW SOS response {ECO:0000256|HAMAP-Rule:MF_00016}. FT DOMAIN 52 183 AAA. {ECO:0000259|SMART:SM00382}. FT NP_BIND 60 67 ATP. {ECO:0000256|HAMAP-Rule:MF_00016}. SQ SEQUENCE 333 AA; 37174 MW; 711CDB90DD9B22EF CRC64; MEERIMDLHA QNQDETFEYS LRPHSLEQYI GQDKVKENLR VFIEAAKMRE EALDHVLLYG PPGLGKTTLA TIIANEMGVE IRTTSGPAIE RPGDLAAILS SLQPGEVLFI DEIHRLPKSV EEVLYPAMED FCLDIVIGKG PGARSVRLDL PPFTLVGATT RAGALSAPLR DRFGVISRLE YYTESQLREI VTRTAQVLDT AIEESAASEI ARRSRGTPRI ANRLLRRVRD FAQVRGDGDI QFGLADYALE LMQVDKVGLD QIDRKLLLGI IEKFKGGPVG LDTIAATIGE ESGTIEDVYE PYLMQIGFMQ RTPRGRIVTE HVYRHFNLEV PNS //