ID A0A1B6EM82_9HEMI Unreviewed; 1039 AA. AC A0A1B6EM82; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 02-JUN-2021, entry version 14. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAS39030.1}; GN ORFNames=g.30423 {ECO:0000313|EMBL:JAS54769.1}, g.30424 GN {ECO:0000313|EMBL:JAS39030.1}; OS Cuerna arida. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Membracoidea; OC Cicadellidae; Cicadellinae; Proconiini; Cuerna. OX NCBI_TaxID=1464854 {ECO:0000313|EMBL:JAS39030.1}; RN [1] {ECO:0000313|EMBL:JAS39030.1} RP NUCLEOTIDE SEQUENCE. RA Tassone E.E.; RT "De novo transcriptome assembly of four potential Pierce s Disease insect RT vectors from Arizona vineyards."; RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the SLC12A transporter family. CC {ECO:0000256|ARBA:ARBA00010593}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GECZ01030739; JAS39030.1; -; Transcribed_RNA. DR EMBL; GECZ01015000; JAS54769.1; -; Transcribed_RNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0015377; F:cation:chloride symporter activity; IEA:InterPro. DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. DR InterPro; IPR004841; AA-permease/SLC12A_dom. DR InterPro; IPR013612; AA_permease_N. DR InterPro; IPR018491; SLC12_C. DR InterPro; IPR002443; SLC12A1/SLC12A2. DR InterPro; IPR004842; SLC12A_fam. DR Pfam; PF00324; AA_permease; 1. DR Pfam; PF08403; AA_permease_N; 1. DR Pfam; PF03522; SLC12; 1. DR PRINTS; PR01207; NAKCLTRNSPRT. DR TIGRFAMs; TIGR00930; 2a30; 1. PE 3: Inferred from homology; KW Ion transport {ECO:0000256|ARBA:ARBA00023065}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Sodium {ECO:0000256|ARBA:ARBA00023053}; KW Sodium transport {ECO:0000256|ARBA:ARBA00023201}; KW Symport {ECO:0000256|ARBA:ARBA00022847}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}. FT TRANSMEM 118..137 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 149..170 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 191..214 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 239..258 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 265..283 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 321..343 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 355..379 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 420..442 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 477..497 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 503..524 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 536..569 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 50..88 FT /note="AA_permease_N" FT /evidence="ECO:0000259|Pfam:PF08403" FT DOMAIN 117..614 FT /note="AA_permease" FT /evidence="ECO:0000259|Pfam:PF00324" FT DOMAIN 623..1039 FT /note="SLC12" FT /evidence="ECO:0000259|Pfam:PF03522" FT REGION 12..50 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 798..820 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 30..50 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1039 AA; 114712 MW; 77649AC478B14EC0 CRC64; MAGRFNVAKA MQKGGGGIDN PAMDMGSIPT GLNLSPSALP DGSQDGLDRS QSQSFCHLTM EALPRADYYK NNRDAIKRPS LGELHGEPRT LDLHQEEKSG IPFDEEHKGM KLGWIQGVLI PCLLNIWGVM LFLRLSWVVG QAGIMQSLLI IAASAIVCVL TTLSMSAICT NGEVKGGGIY YIISRSLGPE FGASVGVIFA FANAVAASMN TIGFCDSLND LLKSHGLKIV DGGLTDVRIV GLIALLVMII ICAVGMEWES KAQNFLVIII ILAIVDFLVG TLVGPHDDLT KAKGFEGFSM DVFKENWGPA YRYSEGLNQD LFTVFAIFFP SVTGIQAGAN ISGDLKDPAG AIPKGTLLAV LISMTSYALF VIFAGGAALR DANGDVNFFY NGSVSNCTLV GGTCDYGLQN SYSVMQLMSA WGALIYAGCF AATLSTALTN LLSVPRLIQA LGIDRIYPGL IFFSKGYGKH GEPYRGYVLV FFISGAFILI AEINVIAPLI SNFYLASYAL INFCTFHAAL VRPLGWRPTF KYYNKWLSLV AFLTCIAIMF LINWLTSIIT FIVFFVLYLV VMYRNPNVNW GSSTQAQTYK RALMTVHKLF NQSEHVKNYQ PQVLLLVGQP QSRPPLVDLA NLVTRNNSLL VCAEIWKQRL TYRQRVALTK QGQAWLAVRK VKGFFQITDG YKFEIAARGL IQCSGVGRLK PNVLMMGYKS DWLTCNTEDL QGYFNVLHDA FENRLAVTIL RLAEGLDLAK PSDLTQYPED VTGSLGDLSG NSNSGNGIVH NDSNLSYILP NVLSQTSLTI PGSKPPERPA NPWQNSPSSA LKEKKKKIAS QILHKYEEGQ EISKAVLDSM MTFSKKHKGG IIDVWWLYDD GGLTILLPYI LSTRSSWADC KMRVFALANR TNELQSEEQG MASLLSKFRI KYTSLTMIHN ISEPPKQETI NFFENIISGF RESNKNAECT VSDMEYEALR EKTYRQLRLR ELLQQHSKQS NLVVMSLPMP RKGVVSAPLY MAWLEAITKD MPPFLLVRGN QTSVLTFYS //