ID A0A1B1M0P9_PLADU Unreviewed; 2946 AA. AC A0A1B1M0P9; DT 02-NOV-2016, integrated into UniProtKB/TrEMBL. DT 02-NOV-2016, sequence version 1. DT 05-JUN-2019, entry version 18. DE SubName: Full=Adenomatous polyposis coli {ECO:0000313|EMBL:ANS60439.1}; OS Platynereis dumerilii (Dumeril's clam worm). OC Eukaryota; Metazoa; Lophotrochozoa; Annelida; Polychaeta; Palpata; OC Aciculata; Phyllodocida; Nereididae; Platynereis. OX NCBI_TaxID=6359 {ECO:0000313|EMBL:ANS60439.1}; RN [1] {ECO:0000313|EMBL:ANS60439.1} RP NUCLEOTIDE SEQUENCE. RA Noorani M.; RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:ANS60439.1} RP NUCLEOTIDE SEQUENCE. RA Simon F.; RT "Beta-catenin controls segment polarity in the annelid Platynereis."; RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KT266548; ANS60439.1; -; mRNA. DR GO; GO:0008013; F:beta-catenin binding; IEA:InterPro. DR GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:InterPro. DR GO; GO:0016055; P:Wnt signaling pathway; IEA:InterPro. DR Gene3D; 1.25.10.10; -; 1. DR InterPro; IPR026818; Apc_fam. DR InterPro; IPR041257; APC_rep. DR InterPro; IPR009223; APC_rpt. DR InterPro; IPR011989; ARM-like. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR000225; Armadillo. DR PANTHER; PTHR12607; PTHR12607; 3. DR Pfam; PF05923; APC_r; 6. DR Pfam; PF18797; APC_rep; 1. DR Pfam; PF00514; Arm; 1. DR SMART; SM00185; ARM; 7. DR SUPFAM; SSF48371; SSF48371; 1. DR PROSITE; PS50176; ARM_REPEAT; 2. PE 2: Evidence at transcript level; FT REPEAT 350 378 ARM. {ECO:0000256|PROSITE-ProRule: FT PRU00259}. FT REPEAT 486 514 ARM. {ECO:0000256|PROSITE-ProRule: FT PRU00259}. FT REGION 239 272 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 666 726 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 741 826 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 886 905 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 946 966 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 994 1057 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1062 1081 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1132 1172 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1220 1356 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1467 1494 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1510 1560 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1598 1656 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1685 1746 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 1861 1941 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 2115 2186 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 2246 2856 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 2868 2903 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT REGION 2917 2946 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 252 266 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 669 683 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 748 770 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 779 793 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 800 826 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 948 966 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1008 1057 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1220 1238 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1248 1265 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1324 1343 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1515 1545 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1713 1733 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 1894 1920 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2115 2146 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2148 2186 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2246 2266 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2273 2294 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2302 2337 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2412 2449 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2538 2602 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2614 2641 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2677 2700 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2715 2735 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2754 2770 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2785 2799 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. FT COMPBIAS 2812 2829 Polar. {ECO:0000256|MobiDB-lite: FT A0A1B1M0P9}. SQ SEQUENCE 2946 AA; 319714 MW; CD882A584B5D088F CRC64; MEKRLQRKQD VLKDMTNVPH FILPLLSRQL GDGEGVVCLD ANNGSPLVTI GTQTLEYQQE EGHEEQEPAN QNLATLYHGA WPTFDKGNAV GNMGPGVAAF PDTASVMSFN SAHTSSTQAN AARTTSNHQL GTKVEMVYSL LSMLGTHDKD DMSRTLLAMS SSQDSCIAMR QSGCLPLLVQ LLHGSDKDSV LGNTRGRKTA RARAAAALHN IVHSHPDDKR GRREARVLRL LEQIRAHCDQ LRDSPDEDED AENQDSNKKA TGHGSADIDH HPGPAIAALM KLSFDEEHRH AICTLGGLQA IAELLQLDHD ANGNTSEQYN ITMRRYACMA LTNLTFGDGT NKALLCSMKT CMKALVAQLQ SSNEDLRQVA ASVLRNLSWR ADLASKKTLR EVGAVVALMK ASMEVSKEST LKSILSALWN LSAHCSENKA DICAVDESLA FLVSTLTYKS PSKTLAIIEN GGGILRNISS HIAIREEYRK VLREHGCLQI LLKHLRSPSL TIVSNACGTL WNLSARCPED QRALWELGAV NMLRNLVHSK HKMISMGSAA ALKNLLAAKP SMMTLDGDKH KQSNMPTLHV RKQRALEAEL DQTLAETCDN VESPSGSPTE QRKHIPVDAS KNFVFGNDNN AYQSGEPDHR RSFVRNQFAR NPSADAAFML EAKMRSPSRP VSRSGSQDSV GSVHSDISHD RVRTHNVLAK SNRLLTERQN MNSDRRMGDR RAGPNSRIVQ VMQEVAIHAG IDGNYMRESH SAENTPPTMR RSQTNPTLRD AANLPPRINN YMKNGQQFSP RHSIAGDTHL AQRLGQQQPT QQQQQQQTQQ SPNEGQIPYQ NITQCMESLH LDDDSSQEQP INYSLKYADG PNQAKQANNV GNFMHELMYN GQSQVPAQNA QSMKSPPHKA NSQYSEFSEQ DNDAMDQPTN YSIRFAEQVD DGHFSDQPIN YSTRFQESGA NEDEEADNTV IHQEQDEMNL DTIRTFCTEG TPYLSTATSM EDLTGIGKED KPKTPQTKAN PESKQYPSHF TESHSSKSTE HQTSSTVVRG KQTESAANIQ NNNVSRVVDT VPQPSLYSYN DNVTASPGSE KPMQYCTEGT PTCFSRVSSL SSLHSTDAHD HPDNNQNRGD LTLQSIDENH SLETTNRQTG GTPMRPDSHN RSLNATNGSI GSGTNTPSHH KSVTFDENNQ VQETPLMFSR CSSLGSLSSF DAHSVHSSVV SDYSRRASEV VSPSELPDSP SDSMPGSPSR KSPVKFDSKL NDSQSTNITQ IRKPVVQQQP PPPANISAAG EESNVQIVRP IPTKTLFADS PKQFGDEGTP DFSCATSLSG LDLDEPDICR DSELERIPLG PEEGEEEAPS SGEPSQLEFT VIEKTENAAE SDNDSVSEGD EDILNEYMMM AMPKRKAKKS SSQSQVAAAD VPRSPYIKVP SGYVNLDIED PMDTIKQYGT EDTPLNYSRD DALSNLSFNS STGELVNLGG LGERESPTND DDDKSDISSI ADDGEDCEDL LSEAIAAAMP KKVAKASKSD NRTAKGQMER PKEGALVKEK HQQQNMRQHS QQQVYPQRGS LSVAARAVSH SVPPQSDCIR TYCEEGTPIN FSRATSLSEL SQLDPDGASQ DHSVGSELDE SDQFDEIPTA YFDGDTSLPV EIMDSPTSFG MEGTPLSFSR NDSLSSLSCD EDAELENAKQ HLKGAKLPLH SKGSPKSLLT PKQRLLGRLK SPGSGSKNRS PGSRAQRNLA FGKPQPQSPL AMSPPRSEYD QIQMFAVEGT PHCFSRNSSL SSLNSTDNDI SANVSDIKGD EDAQQACSSG DTSAEQEHIE GQLPPDSFYV EDTPANFSRN SSLSSLSVES LGFEPSEAAL LEECINAAMP KTKSAKKKVS KIPRNCPTST PKDKFVKPRT PPSGNQPKVK TPSPSREGSP KNVQSSQHGN EVERTRVEEQ NTSEHPQLTI ENVVWRHRSP SQELEGSPKL LKDASNQEKV LGALMMESED KNSEEKDDSQ VKGLVFDFDN KLYISESDLD NKNDVEDYNN KLVDMELANS DMIASAIFRE ASEIAEGFAE AAQLEDESCS ESDYPIVAKE EIEATKENPV VEGDEQLGCF PIDCSFHDIT KETFPDMGLS LGSSMMSSVG DDNQVTVRSK SSTGASVRNV SNETDLSLDE GVGHDDSNDT AIEDDDSKRF SDVTEGSDTN SHEITLEEEQ ALEENAELLI RELSNVHLSQ LSSSVNSEMF IENETISLVS NDTDTCSEVS VSLSCSSKAM SEKTNEDSNA SSSAASRPRI LKPGERSSLE VKAKEEEVKA VRGKRKPLTS RVNSGRPPSV SSPMKNDTKS KKTTPPTKPN TVKSKPPVGN TKVIPKTPSK VTPAAKSNVT PAAKAAPKMK PLAGKPTAGV KPTPKASAVV APMTKNTNAT RAAARKPSPA RSGTASPRNQ SPADKMRNKT TTKEPSSLAS TNVKKPQSKV TSALIKGKAK NSGKVNNNEA DRPKPPIKQG TFTKDSPTQN APEIEGDDNE DIKDDSPSSN RSSAELKYSN DTQEKAPGEK ISPRSSKADA AGPSSTPPAV ANLKQNGSQK AVAGKSNSTG NLTKTTKSVT KTASGSNLTK TGSNTSLTKG SGTFKVPKAP LKKGDSMSNQ SLKKDSSKPG TSVTTPKKGT GNDKTGGRAT VPVASKIASL WRKGDSKTAS PSKAGPEKKT PLKKEKEKTP AAKSETKPKF LRRSLASSQP SKGAKEDGKQ SKTPNKKDDK GMQRSSTYDK LPVNEGEAES AEKAETSSGG SPAKNNVWRR TYTIENEEEV LQAVTTDDCE TSNSPGVWMR RDNDRTPVKS QIPAPVRSSP EQSGDGRGNK PSPPSAFPNK SGLGISPPGA KPTVTSPNAA IVAPFNYVPT QSLNNKPVSS ANDENDLKGM KPNNGTDSPT RPMTKTEMLI ARRRQSYLNS VNKSGEEQKT SEEDESKRTA CLVTTV //