ID A0A1B0GV43_HUMAN Unreviewed; 423 AA. AC A0A1B0GV43; DT 05-OCT-2016, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 1. DT 02-NOV-2016, entry version 2. DE SubName: Full=Neuronal acetylcholine receptor subunit alpha-7 {ECO:0000313|Ensembl:ENSP00000490365}; GN Name=CHRNA7 {ECO:0000313|Ensembl:ENSP00000490365}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000490365, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000490365, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16572171; DOI=10.1038/nature04601; RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S., RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., RA Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., RA Nusbaum C.; RT "Analysis of the DNA sequence and duplication history of human RT chromosome 15."; RL Nature 440:671-675(2006). RN [2] {ECO:0000313|Ensembl:ENSP00000490365} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2016) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSP00000490365}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ABBA01038340; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC058803; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC068448; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC079969; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF456018; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF456023; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF573652; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENST00000637183; ENSP00000490365; ENSG00000175344. DR HGNC; HGNC:1960; CHRNA7. DR OpenTargets; ENSG00000175344; -. DR GeneTree; ENSGT00790000122957; -. DR Proteomes; UP000005640; Chromosome 15. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 152 177 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 183 201 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 213 236 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 391 411 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 423 AA; 47434 MW; 38D69334AE8BAF63 CRC64; MSWTDHYLQW NVSEYPGVKT VRFPDGQIWK PDILLYNSAD ERFDATFHTN VLVNSSGHCQ YLPPGIFKSS CYIDVRWFPF DVQHCKLKFG SWSYGGWSLD LQMQEADISG YIPNGEWDLV GIPGKRSERF YECCKEPYPD VTFTVTMRRR TLYYGLNLLI PCVLISALAL LVFLLPADSG EKISLGITVL LSLTVFMLLV AEIMPATSDS VPLIAQYFAS TMIIVGLSVV VTVIVLQYHH HDPDGGKMPK WTRVILLNWC AWFLRMKRPG EDKVRPACQH KQRRCSLASV EMSAVAPPPA SNGNLLYIGF RGLDGVHCVP TPDSGVVCGR MACSPTHDEH LLHGGQPPEG DPDLAKILEE VRYIANRFRC QDESEAVCSE WKFAACVVDR LCLMAFSVFT IICTIGILMS APNFVEAVSK DFA //