ID A0A180A6U5_LACRH Unreviewed; 839 AA. AC A0A180A6U5; DT 07-SEP-2016, integrated into UniProtKB/TrEMBL. DT 07-SEP-2016, sequence version 1. DT 19-JAN-2022, entry version 27. DE RecName: Full=Galactosylceramidase {ECO:0000256|ARBA:ARBA00018762}; DE EC=3.2.1.46 {ECO:0000256|ARBA:ARBA00012657}; GN ORFNames=CCE29_06885 {ECO:0000313|EMBL:ART95700.1}, GFB59_00325 GN {ECO:0000313|EMBL:QPB46449.1}, PY74_08650 GN {ECO:0000313|EMBL:OAU75264.1}; OS Lacticaseibacillus rhamnosus (Lactobacillus rhamnosus). OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lacticaseibacillus. OX NCBI_TaxID=47715 {ECO:0000313|EMBL:OAU75264.1, ECO:0000313|Proteomes:UP000078251}; RN [1] {ECO:0000313|EMBL:OAU75264.1, ECO:0000313|Proteomes:UP000078251} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Lrh29 {ECO:0000313|EMBL:OAU75264.1, RC ECO:0000313|Proteomes:UP000078251}; RA Ceapa C., Ritari J.; RT "The variable regions of Lactobacillus rhamnosus genomes reveal the dynamic RT evolution of metabolic and host-adaptation repertoires."; RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:ART95700.1, ECO:0000313|Proteomes:UP000195731} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=4B15 {ECO:0000313|EMBL:ART95700.1, RC ECO:0000313|Proteomes:UP000195731}; RA Oh N.-S.; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:QPB46449.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TK-F8B {ECO:0000313|EMBL:QPB46449.1}; RA Chen H.; RT "Whole genome of Lactobacillus rhamnosus TK-F8B."; RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 59 family. CC {ECO:0000256|ARBA:ARBA00005637}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP021426; ART95700.1; -; Genomic_DNA. DR EMBL; JTIA01000220; OAU75264.1; -; Genomic_DNA. DR EMBL; CP045586; QPB46449.1; -; Genomic_DNA. DR RefSeq; WP_014568910.1; NZ_WKOZ01000004.1. DR EnsemblBacteria; ART95700; ART95700; CCE29_06885. DR Proteomes; UP000078251; Unassembled WGS sequence. DR Proteomes; UP000195731; Chromosome. DR Proteomes; UP000663681; Chromosome. DR GO; GO:0004336; F:galactosylceramidase activity; IEA:InterPro. DR GO; GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. DR Gene3D; 3.20.20.70; -; 1. DR InterPro; IPR013785; Aldolase_TIM. DR InterPro; IPR001286; Glyco_hydro_59. DR InterPro; IPR017853; Glycoside_hydrolase_SF. DR PANTHER; PTHR15172; PTHR15172; 1. DR Pfam; PF02057; Glyco_hydro_59; 1. DR SUPFAM; SSF51445; SSF51445; 1. PE 3: Inferred from homology; KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963}; KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963}; KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919}. SQ SEQUENCE 839 AA; 92976 MW; 7439A784F6859C5E CRC64; MHTLTIDGSQ LQLEQNEANT IKGFGLLSCN NTSRLLMDYK WEQPEVYQQV LQHLFGGQQP LMRMLKVELG SDSNTSCGTE PAPQRAADEP ANVARGMGFQ LIADAKKIQP DLKTCMLRWA EPGFLRPSWR QVKSDDPDEK VPTEAFEAMY QYYKQTVIAA WQAYGYLFDY IDPDRNETKH PMYRYLKWFA NRLKTDQADF PEGFPVADYH AIKLITSDQN YGTDMGTALL NDPELQAVIP AVGYHYNTDD GPDKPFTKIA DQLHKEVWYS EGIAPVTFGT LRTQDTTGIG IGGPMSALDV ANRLVKSYAR SRRSLYIFQP AIGGLYPGAK YPGKQLLEMD TPWSGYFQQD TVALAVMHHF TDFAVTGWRD QTAAKNWRYV PSATVSEVAG TENLTQAFGA ASVMTLVAPD ETDYTVMLIN DTSAPQTYQI TVKNLAAATK PLYVWQTWAD DAGKIHDREK TTTLTPVNGN VTVTIEPRAI ISATTTDFQP QALLPNPDVK TDQPLQQDPE NHVLFHDDYT YADMPADYLT RRGGTPKYTT DMDGAFEVVE QDGKRGLQQK ITEQSRALAW ETQTDPNFTV GDIRWLNYAA ALKFTFDTTT RQNTVSANYI GLGVRSVDDF EGSLFSAPYV ATLTVGGKLR FYVRGALAAT LDVPVFDAEV SHELIVEATD RHVTVQIDGQ TYVTYDDPSD QPGLAGQVKV GTGYFKTVIQ ALTVTSTSAP AVLGHRRDDL DASLTFSDDQ WERLAARFPH AWERSQSIGE KGATVDFDVE GTGFVLFGTQ AHASRLQLAV DGRIQEVVPL TALAKQPNTV VTDLAAGPHH VKVTVIDGSY TFDGVAPIL //