ID A0A178CH59_9EURO Unreviewed; 142 AA. AC A0A178CH59; DT 07-SEP-2016, integrated into UniProtKB/TrEMBL. DT 07-SEP-2016, sequence version 1. DT 03-AUG-2022, entry version 25. DE RecName: Full=Mediator of RNA polymerase II transcription subunit 31 {ECO:0000256|ARBA:ARBA00019660, ECO:0000256|RuleBase:RU364129}; GN ORFNames=AYO22_02859 {ECO:0000313|EMBL:OAL28405.1}; OS Fonsecaea multimorphosa. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea. OX NCBI_TaxID=979981 {ECO:0000313|EMBL:OAL28405.1, ECO:0000313|Proteomes:UP000185698}; RN [1] {ECO:0000313|EMBL:OAL28405.1, ECO:0000313|Proteomes:UP000185698} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 980.96 {ECO:0000313|EMBL:OAL28405.1, RC ECO:0000313|Proteomes:UP000185698}; RA Leao A.C., Weiss V.A., Vicente V.A., Pedrosa F.O., Steffens M.B., Faoro H., RA Tadra-Sfeir M.Z., Raittz R.T., Najafzadeh M.J., Felipe M.S., Teixeira M., RA Gomes R., Moreno L.F., Gorbushina A., De Hoog S., De Souza E.M.; RT "The draft genome sequence of Fonsecaea multimorphosa, causative agent of RT systemic infection in an animal host."; RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in CC the regulated transcription of nearly all RNA polymerase II-dependent CC genes. Mediator functions as a bridge to convey information from gene- CC specific regulatory proteins to the basal RNA polymerase II CC transcription machinery. Mediator is recruited to promoters by direct CC interactions with regulatory proteins and serves as a scaffold for the CC assembly of a functional preinitiation complex with RNA polymerase II CC and the general transcription factors. {ECO:0000256|RuleBase:RU364129}. CC -!- SUBUNIT: Component of the Mediator complex. CC {ECO:0000256|RuleBase:RU364129}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|RuleBase:RU364129}. CC -!- SIMILARITY: Belongs to the Mediator complex subunit 31 family. CC {ECO:0000256|ARBA:ARBA00006378, ECO:0000256|RuleBase:RU364129}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OAL28405.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LVCI01000038; OAL28405.1; -; Genomic_DNA. DR EnsemblFungi; OAL28405; OAL28405; AYO22_02859. DR Proteomes; UP000185698; Unassembled WGS sequence. DR GO; GO:0016592; C:mediator complex; IEA:InterPro. DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro. DR Gene3D; 1.10.10.1340; -; 1. DR InterPro; IPR038089; Med31_sf. DR InterPro; IPR008831; Mediator_Med31. DR PANTHER; PTHR13186; PTHR13186; 1. DR Pfam; PF05669; Med31; 1. PE 3: Inferred from homology; KW Activator {ECO:0000256|RuleBase:RU364129}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364129}; KW Transcription {ECO:0000256|RuleBase:RU364129}; KW Transcription regulation {ECO:0000256|RuleBase:RU364129}. FT REGION 119..142 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 142 AA; 16142 MW; B9BA5E5CEBE25AFA CRC64; MDGGGPPTAL SHRFTLELEF VLCLSNPLYL QYLALNFPHL LNKPATSQNP TEADNSDAAR FARYLKYLYN YWRTPEYAKY LTHPGATLRN LELLQQEQFR KDIIRPDVIA KLFETDVAQQ DAPDVTDEKD PSTQQVSGDA GH //