ID A0A172LR40_SORCA Unreviewed; 379 AA.
AC A0A172LR40;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 31-JAN-2018, entry version 9.
DE RecName: Full=Cytochrome b {ECO:0000256|RuleBase:RU362117};
GN Name=cytb {ECO:0000313|EMBL:ANA78326.1};
OS Sorex caecutiens (Laxmann's shrew).
OG Mitochondrion {ECO:0000313|EMBL:ANA78326.1}.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Laurasiatheria; Insectivora; Soricidae; Soricinae;
OC Sorex.
OX NCBI_TaxID=62276 {ECO:0000313|EMBL:ANA78326.1};
RN [1] {ECO:0000313|EMBL:ANA78326.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KT3714KTF536 {ECO:0000313|EMBL:ANA78326.1}, and KTF3713KTF535
RC {ECO:0000313|EMBL:ANA78325.1};
RC TISSUE=Lung {ECO:0000313|EMBL:ANA78326.1};
RX PubMed=27172519;
RA Arai S., Kang H.J., Gu S.H., Ohdachi S.D., Cook J.A., Yashina L.N.,
RA Tanaka-Taya K., Abramov S.A., Morikawa S., Okabe N., Oishi K.,
RA Yanagihara R.;
RT "Genetic Diversity of Artybash Virus in the Laxmann's Shrew (Sorex
RT caecutiens).";
RL Vector Borne Zoonotic Dis. 0:0-0(2016).
CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase
CC complex (complex III or cytochrome b-c1 complex) that is part of
CC the mitochondrial respiratory chain. The b-c1 complex mediates
CC electron transfer from ubiquinol to cytochrome c. Contributes to
CC the generation of a proton gradient across the mitochondrial
CC membrane that is then used for ATP synthesis.
CC {ECO:0000256|RuleBase:RU362117}.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|RuleBase:RU362117};
CC Note=Binds 2 heme groups non-covalently.
CC {ECO:0000256|RuleBase:RU362117};
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU362117}.
CC -!- SIMILARITY: Belongs to the cytochrome b family.
CC {ECO:0000256|RuleBase:RU362117}.
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DR EMBL; KU760883; ANA78325.1; -; Genomic_DNA.
DR EMBL; KU760884; ANA78326.1; -; Genomic_DNA.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045275; C:respiratory chain complex III; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro.
DR GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro.
DR CDD; cd00290; cytochrome_b_C; 1.
DR CDD; cd00284; Cytochrome_b_N; 1.
DR Gene3D; 1.20.810.10; -; 1.
DR InterPro; IPR005798; Cyt_b/b6_C.
DR InterPro; IPR036150; Cyt_b/b6_C_sf.
DR InterPro; IPR005797; Cyt_b/b6_N.
DR InterPro; IPR027387; Cytb/b6-like_sf.
DR InterPro; IPR030689; Cytochrome_b.
DR InterPro; IPR016174; Di-haem_cyt_TM.
DR Pfam; PF00032; Cytochrom_B_C; 1.
DR Pfam; PF00033; Cytochrome_B; 1.
DR PIRSF; PIRSF038885; COB; 1.
DR SUPFAM; SSF81342; SSF81342; 1.
DR SUPFAM; SSF81648; SSF81648; 1.
DR PROSITE; PS51003; CYTB_CTER; 1.
DR PROSITE; PS51002; CYTB_NTER; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|RuleBase:RU362117};
KW Heme {ECO:0000256|RuleBase:RU362117};
KW Iron {ECO:0000256|RuleBase:RU362117};
KW Membrane {ECO:0000256|RuleBase:RU362117};
KW Metal-binding {ECO:0000256|RuleBase:RU362117};
KW Mitochondrion {ECO:0000256|RuleBase:RU362117,
KW ECO:0000313|EMBL:ANA78326.1};
KW Respiratory chain {ECO:0000256|RuleBase:RU362117};
KW Transmembrane {ECO:0000256|RuleBase:RU362117};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362117};
KW Transport {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 30 56 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 77 98 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 113 133 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 140 158 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 178 200 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 229 247 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 288 307 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 319 340 Helical. {ECO:0000256|RuleBase:RU362117}.
FT TRANSMEM 346 372 Helical. {ECO:0000256|RuleBase:RU362117}.
FT DOMAIN 1 209 CYTB_NTER. {ECO:0000259|PROSITE:PS51002}.
FT DOMAIN 210 379 CYTB_CTER. {ECO:0000259|PROSITE:PS51003}.
SQ SEQUENCE 379 AA; 42691 MW; DC8C1A9A3267CD86 CRC64;
MTNLRKTHPL MKIVNSSFID LPAPSNISSW WNFGSLLGVC LIIQILTGLF LAMHYTSDTM
TAFSSVTHIC RDVNYGWLIR YLHANGASMF FICLFLHVGR GLYYGSYMYL ETWNIGVLLL
FAVMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGSDL VEWIWGGFSV DKATLTRFFA
FHFILPFIVA ALAGVHLLFL HETGSNNPSG LCSDADKIPF HPYYTIKDIL GVLLFILILT
SLVLFSPDLL GDPDNYMPAN PLNTPPHIKP EWYFLFAYAI LRSIPNKLGG VLALALSILI
LALVPFLHTS KQRSMMFRPF SQCLFWILVA DLLTLTWIGG QPVEHPFIII GQLASILYFL
LILVIMPITS LFENNLLKW
//