ID A0A151LE76_9APIC Unreviewed; 501 AA. AC A0A151LE76; DT 08-JUN-2016, integrated into UniProtKB/TrEMBL. DT 08-JUN-2016, sequence version 1. DT 08-NOV-2023, entry version 23. DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099}; DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099}; GN ORFNames=PGSY75_1351600 {ECO:0000313|EMBL:KYN97284.1}; OS Plasmodium gaboni. OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; OC Plasmodiidae; Plasmodium; Plasmodium (Laverania). OX NCBI_TaxID=647221 {ECO:0000313|EMBL:KYN97284.1, ECO:0000313|Proteomes:UP000076004}; RN [1] {ECO:0000313|EMBL:KYN97284.1, ECO:0000313|Proteomes:UP000076004} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SY75 {ECO:0000313|EMBL:KYN97284.1, RC ECO:0000313|Proteomes:UP000076004}; RX PubMed=27002652; DOI=10.1038/ncomms11078; RA Sundararaman S.A., Plenderleith L.J., Liu W., Loy D.E., Learn G.H., Li Y., RA Shaw K.S., Ayouba A., Peeters M., Speede S., Shaw G.M., Bushman F.D., RA Brisson D., Rayner J.C., Sharp P.M., Hahn B.H.; RT "Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary RT events leading to human malaria."; RL Nat. Commun. 7:11078-11078(2016). CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. CC {ECO:0000256|ARBA:ARBA00005190}. CC -!- SIMILARITY: Belongs to the FGGY kinase family. CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KYN97284.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LVLB01000014; KYN97284.1; -; Genomic_DNA. DR RefSeq; XP_018640289.1; XM_018787547.1. DR AlphaFoldDB; A0A151LE76; -. DR EnsemblProtists; KYN97284; KYN97284; PGSY75_1351600. DR GeneID; 29778136; -. DR KEGG; pgab:PGSY75_1351600; -. DR VEuPathDB; PlasmoDB:PGABG01_1349600; -. DR VEuPathDB; PlasmoDB:PGSY75_1351600; -. DR OrthoDB; 2734344at2759; -. DR UniPathway; UPA00618; UER00672. DR Proteomes; UP000076004; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC. DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway. DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro. DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW. DR CDD; cd07769; FGGY_GK; 1. DR Gene3D; 3.30.420.40; -; 2. DR InterPro; IPR043129; ATPase_NBD. DR InterPro; IPR000577; Carb_kinase_FGGY. DR InterPro; IPR018485; Carb_kinase_FGGY_C. DR InterPro; IPR018483; Carb_kinase_FGGY_CS. DR InterPro; IPR018484; Carb_kinase_FGGY_N. DR InterPro; IPR005999; Glycerol_kin. DR NCBIfam; TIGR01311; glycerol_kin; 1. DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1. DR PANTHER; PTHR10196; SUGAR KINASE; 1. DR Pfam; PF02782; FGGY_C; 1. DR Pfam; PF00370; FGGY_N; 1. DR PIRSF; PIRSF000538; GlpK; 1. DR SUPFAM; SSF53067; Actin-like ATPase domain; 2. DR PROSITE; PS00933; FGGY_KINASES_1; 1. DR PROSITE; PS00445; FGGY_KINASES_2; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798}; KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:KYN97284.1}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}; KW Transferase {ECO:0000256|RuleBase:RU003733}. FT DOMAIN 3..253 FT /note="Carbohydrate kinase FGGY N-terminal" FT /evidence="ECO:0000259|Pfam:PF00370" FT DOMAIN 262..452 FT /note="Carbohydrate kinase FGGY C-terminal" FT /evidence="ECO:0000259|Pfam:PF02782" SQ SEQUENCE 501 AA; 56780 MW; 17BF6F9DF897C9F1 CRC64; MNVILSIDQS TQSTKVFFYD EELNIVHSNN LNHEQKCLKP GWYEHDPIEI MNNLYDLMNE GIKVLKDKYT SVIIKCIGIT NQRETVIIWD RITGKPLYNA IVWLDTRVEE LVTEFSEKYN NNDIQKKTGT HFNTYFSAFK ILWLIQNKPE IKQKIDDGTA VIGNINTWLI FNLTKGNCYT DVTNASRTLL MDINTLQWDE KMCKIFNITN MSVLPEIKSN CSNFGLVKSE RVPDYLNIPI TGCIGDQQSA CIGQAIFDEG EAKCTYGTGV FLLINTGEKV VYSTCGLITT VCYKFNDNDK PKYALEGSIG TAGSGVSWLL KNKLIDDPSE ASDIMEKCEN TTGVIFVPAF SGLYAPRWRS DARASIYGMT FNTERSHIVR ALLEGIAFQL NEIVDSLTSD MGIEMLHVLR CDGGMTKNKP FMQFNSDIIN TKIEVSKYKE VTSLGAAVLA GLEVKIWDSL DSVKSLLRRS DAVFHSKMDD KNRKKKTYEW NKAVERTLIQ L //