ID A0A142AHG6_9CALI Unreviewed; 249 AA. AC A0A142AHG6; DT 08-JUN-2016, integrated into UniProtKB/TrEMBL. DT 08-JUN-2016, sequence version 1. DT 07-SEP-2016, entry version 3. DE SubName: Full=RNA-dependent RNA polymerase protein {ECO:0000313|EMBL:AMO28409.1}; DE Flags: Fragment; OS Norovirus GII. OC Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; OC Caliciviridae; Norovirus. OX NCBI_TaxID=122929 {ECO:0000313|EMBL:AMO28409.1}; RN [1] {ECO:0000313|EMBL:AMO28409.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Norovirus GII/Hu/KR/2015/GII.P21_GII.21/20150321_GL02BLP3 RC {ECO:0000313|EMBL:AMO28409.1}; RA Koo E.S., Kim M.S., Choi Y.S., Jeong Y.S.; RT "Occurrence of the Novel Human Norovirus in Coastal Stream Water of RT South Korea, 2015."; RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). {ECO:0000256|SAAS:SAAS00519153}. CC -!- SIMILARITY: Contains RdRp catalytic domain. CC {ECO:0000256|SAAS:SAAS00519020}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KU687031; AMO28409.1; -; Genomic_RNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004386; F:helicase activity; IEA:InterPro. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro. DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro. DR InterPro; IPR004004; Helic/Pol/Pept_Calicivir-typ. DR InterPro; IPR001205; RNA-dir_pol_C. DR InterPro; IPR007094; RNA-dir_pol_PSvirus. DR Pfam; PF00680; RdRP_1; 1. DR PRINTS; PR00918; CALICVIRUSNS. DR PROSITE; PS50507; RDRP_SSRNA_POS; 1. PE 4: Predicted; KW Nucleotidyltransferase {ECO:0000256|SAAS:SAAS00519240}; KW RNA-directed RNA polymerase {ECO:0000256|SAAS:SAAS00519100, KW ECO:0000313|EMBL:AMO28409.1}; KW Transferase {ECO:0000256|SAAS:SAAS00519135}. FT DOMAIN 1 96 RdRp catalytic. {ECO:0000259|PROSITE: FT PS50507}. FT NON_TER 1 1 {ECO:0000313|EMBL:AMO28409.1}. SQ SEQUENCE 249 AA; 28018 MW; 66574712731CA476 CRC64; MVKFSPEPHL AQVVAEDLLS PSVMDVGDFK ISINEGLPSG VPCTSQWNSI AHWLLTLCAL SEVTDLSPDI IQANSLFSFY GDDEIVSTDI KLDPEKLTVK LKEYGLKPTR PDKTEGPLII SEDLDGLTFL RRTVTRDPAG WFGKLDQSSI LRQMYWTRGP NHEDPSETMI PHSQRPIQLM SLLGEAALHG PSFYSKISKL VISELKEGGM DFYVPRQEPM FRWMRFSDLS TWEGDRNLAP SFVNEDGVE //