ID A0A140LJ48_MOUSE Unreviewed; 133 AA. AC A0A140LJ48; DT 11-MAY-2016, integrated into UniProtKB/TrEMBL. DT 11-MAY-2016, sequence version 1. DT 28-FEB-2018, entry version 8. DE SubName: Full=Diacylglycerol O-acyltransferase 2 {ECO:0000313|Ensembl:ENSMUSP00000147074}; GN Name=Dgat2 {ECO:0000313|Ensembl:ENSMUSP00000147074, GN ECO:0000313|MGI:MGI:1915050}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000147074}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000147074, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000147074, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000147074} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000147074}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000147074}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC115850; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000208591; ENSMUSP00000147074; ENSMUSG00000030747. DR MGI; MGI:1915050; Dgat2. DR GeneTree; ENSGT00750000117391; -. DR ChiTaRS; Dgat2; mouse. DR Proteomes; UP000000589; Chromosome 7. DR ExpressionAtlas; A0A140LJ48; baseline and differential. DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:Ensembl. DR GO; GO:0005811; C:lipid droplet; IEA:Ensembl. DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl. DR GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:Ensembl. DR GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:Ensembl. DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl. DR GO; GO:0071400; P:cellular response to oleic acid; IEA:Ensembl. DR GO; GO:0035356; P:cellular triglyceride homeostasis; IEA:Ensembl. DR GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl. DR GO; GO:0046339; P:diacylglycerol metabolic process; IEA:Ensembl. DR GO; GO:0060613; P:fat pad development; IEA:Ensembl. DR GO; GO:0055089; P:fatty acid homeostasis; IEA:Ensembl. DR GO; GO:0019915; P:lipid storage; IEA:Ensembl. DR GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; IEA:Ensembl. DR GO; GO:0034383; P:low-density lipoprotein particle clearance; IEA:Ensembl. DR GO; GO:0019432; P:triglyceride biosynthetic process; IEA:Ensembl. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 73 98 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 133 AA; 14340 MW; 3EC4B86CA53B6316 CRC64; MKTLIAAYSG VLRGERRAEA ARSENKNKGS ALSREGSGRW GTGSSILSAL QDIFSVTWLN RSKVEKQLQV ISVLQWVLSF LVLALTCPTY LPLVLWAARS SCPSYSQSSL SASQEQEWPA VSSSCTPSAQ TAG //