ID A0A140LHN1_MOUSE Unreviewed; 423 AA. AC A0A140LHN1; DT 11-MAY-2016, integrated into UniProtKB/TrEMBL. DT 11-MAY-2016, sequence version 1. DT 08-JUN-2016, entry version 2. DE SubName: Full=Protein Nrg1 {ECO:0000313|Ensembl:ENSMUSP00000146478}; GN Name=Nrg1 {ECO:0000313|Ensembl:ENSMUSP00000146478}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000146478}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000146478, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146478, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000146478} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146478}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000146478}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC113586; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC127369; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC127374; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC132256; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC132407; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC133091; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC134895; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC136147; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000208598; ENSMUSP00000146478; ENSMUSG00000062991. DR MGI; MGI:96083; Nrg1. DR Proteomes; UP000000589; Chromosome 8. DR Gene3D; 2.60.40.10; -; 1. DR InterPro; IPR013032; EGF-like_CS. DR InterPro; IPR000742; EGF-like_dom. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR013098; Ig_I-set. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR003598; Ig_sub2. DR InterPro; IPR002154; Neuregulin_C. DR InterPro; IPR018250; NRG1. DR PANTHER; PTHR11100:SF7; PTHR11100:SF7; 1. DR Pfam; PF00008; EGF; 1. DR Pfam; PF07679; I-set; 1. DR Pfam; PF02158; Neuregulin; 1. DR PRINTS; PR01089; NEUREGULIN. DR SMART; SM00181; EGF; 1. DR SMART; SM00409; IG; 1. DR SMART; SM00408; IGc2; 1. DR SUPFAM; SSF48726; SSF48726; 1. DR PROSITE; PS00022; EGF_1; 1. DR PROSITE; PS01186; EGF_2; 1. DR PROSITE; PS50026; EGF_3; 1. DR PROSITE; PS50835; IG_LIKE; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|MaxQB:A0A140LHN1}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 243 264 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 423 AA; 46576 MW; 2AA34373111BF5F8 CRC64; MSERKEGRGK GKGKKKDRGS RGKPAPAEGD PSPALPPRLK EMKSQESAAG SKLVLRCETS SEYSSLRFKW FKNGNELNRR NKPQNVKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN DSASANITIV ESNDLTTGMS ASTERPYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLI KCAEKEKTFC VNGGECFMVK DLSNPSRYLC KCQPGFTGAR CTENVPMKVQ TQEKAEELYQ KRVLTITGIC IALLVVGIMC VVAYCKTKKQ RQKLHDRLRQ SLRSERNNMV NIANGPHHPN PPPENVQLVN QYVSKNVISS EHIVEREVET SFSTSHYTST AHHSTTVTQT PSHSWSNGHT ESIISESHSV IMMSSVENSR HSSPAGGPRG RLHGLGGPRE CNSFLRHARE TPDSYRDSPH SER //