ID A0A126GVC9_HUMAN Unreviewed; 318 AA. AC A0A126GVC9; DT 11-MAY-2016, integrated into UniProtKB/TrEMBL. DT 11-MAY-2016, sequence version 1. DT 15-MAR-2017, entry version 10. DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047}; GN Name=OR13C4 {ECO:0000313|EMBL:ALI87368.1}; GN ORFNames=hCG_1804868 {ECO:0000313|EMBL:EAW58981.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ALI87368.1}; RN [1] {ECO:0000313|EMBL:EAW58981.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=11181995; DOI=10.1126/science.1058040; RA Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., RA Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., RA Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., RA Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G., RA Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., RA Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., RA Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., RA Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., RA Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., RA Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., RA Brandon R., Cargill M., Chandramouliswaran I., Charlab R., RA Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., RA Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., RA Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., RA Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., RA Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., RA Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., RA Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., RA Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., RA Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., RA Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., RA Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., RA Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., RA Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., RA Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., RA Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., RA Kline L., Koduru S., Love A., Mann F., May D., McCawley S., RA McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., RA Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., RA Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., RA Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., RA Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., RA Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., RA Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., RA Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., RA Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., RA Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., RA Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., RA Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., RA Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., RA Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., RA Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., RA Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., RA McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., RA Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., RA Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., RA Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.; RT "The sequence of the human genome."; RL Science 291:1304-1351(2001). RN [2] {ECO:0000313|EMBL:EAW58981.1} RP NUCLEOTIDE SEQUENCE. RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., RA Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:ALI87368.1} RP NUCLEOTIDE SEQUENCE. RA Mainland J.D., Li Y.R., Zhou T., Liu W.L.L., Matsunami H.; RT "Human Olfactory Receptor Responses to Odorants."; RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00521146}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047, CC ECO:0000256|SAAS:SAAS00521146}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00591716}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KP290184; ALI87368.1; -; Genomic_DNA. DR EMBL; CH471105; EAW58981.1; -; Genomic_DNA. DR RefSeq; NP_001001919.1; NM_001001919.1. DR UniGene; Hs.553601; -. DR GeneID; 138804; -. DR KEGG; hsa:138804; -. DR CTD; 138804; -. DR KO; K04257; -. DR OMA; EGLVSMF; -. DR PhylomeDB; A0A126GVC9; -. DR ExpressionAtlas; A0A126GVC9; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR InterPro; IPR000725; Olfact_rcpt. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00245; OLFACTORYR. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00521172}; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00529918}; KW Membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00520964}; KW Olfaction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00521184}; KW Receptor {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00529932, ECO:0000313|EMBL:EAW58981.1}; KW Sensory transduction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00521191}; KW Transducer {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00520921}; KW Transmembrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00520995}; KW Transmembrane helix {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00520911}. FT TRANSMEM 25 48 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 60 86 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 92 118 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 139 158 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 204 226 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 238 259 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 279 298 Helical. {ECO:0000256|RuleBase:RU363047}. FT DOMAIN 41 296 G_PROTEIN_RECEP_F1_2. FT {ECO:0000259|PROSITE:PS50262}. SQ SEQUENCE 318 AA; 35576 MW; A2E9E00E9D2F818B CRC64; MDKINQTFVR EFILLGLSGY PKLEIIFFAL ILVMYVVILI GNGVLIIASI LDSRLHMPMY FFLGNLSFLD ICYTTSSIPS TLVSLISKKR NISFSGCAVQ MFFGFAMGST ECFLLGMMAF DRYVAICNPL RYPIIMNKVV YVLLTSVSWL SGGINSTVQT SLAMRWPFCG NNIINHFLCE ILAVLKLACS DISVNIVTLA VSNIAFLVLP LLVIFFSYMF ILYTILRTNS ATGRHKAFST CSAHLTVVII FYGTIFFMYA KPKSQDLLGK DNLQATEGLV SMFYGVVTPM LNPIIYSLRN KDVKAAIKYL LSRKAINQ //