ID   A0A0X8GLL6_HUMAN        Unreviewed;       174 AA.
AC   A0A0X8GLL6;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   07-APR-2021, entry version 30.
DE   SubName: Full=Gamma-crystallin C {ECO:0000313|EMBL:AMC33104.1};
GN   Name=CRYGC {ECO:0000313|EMBL:AMC33104.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AMC33104.1};
RN   [1] {ECO:0000313|EMBL:AMC33104.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Lens {ECO:0000313|EMBL:AMC33104.1};
RA   Rajkumar S., Ekta P.A.;
RT   "Functional candidate gene approach to study genetic polymorphisms in lens
RT   specific genes.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the beta/gamma-crystallin family.
CC       {ECO:0000256|ARBA:ARBA00009646}.
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DR   EMBL; KT455014; AMC33104.1; -; mRNA.
DR   RefSeq; NP_066269.1; NM_020989.3.
DR   RefSeq; XP_011508964.1; XM_011510662.1.
DR   SMR; A0A0X8GLL6; -.
DR   Antibodypedia; 34194; 165 antibodies.
DR   DNASU; 1420; -.
DR   GeneID; 1420; -.
DR   KEGG; hsa:1420; -.
DR   CTD; 1420; -.
DR   OMA; QQYLLRP; -.
DR   OrthoDB; 1220704at2759; -.
DR   PhylomeDB; A0A0X8GLL6; -.
DR   BioGRID-ORCS; 1420; 8 hits in 989 CRISPR screens.
DR   GenomeRNAi; 1420; -.
DR   ExpressionAtlas; A0A0X8GLL6; baseline and differential.
DR   InterPro; IPR001064; Beta/gamma_crystallin.
DR   InterPro; IPR011024; G_crystallin-like.
DR   Pfam; PF00030; Crystall; 2.
DR   PRINTS; PR01367; BGCRYSTALLIN.
DR   SMART; SM00247; XTALbg; 2.
DR   SUPFAM; SSF49695; SSF49695; 1.
DR   PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 4.
PE   2: Evidence at transcript level;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          2..40
FT                   /note="Beta/gamma crystallin 'Greek key'"
FT                   /evidence="ECO:0000259|PROSITE:PS50915"
FT   DOMAIN          41..83
FT                   /note="Beta/gamma crystallin 'Greek key'"
FT                   /evidence="ECO:0000259|PROSITE:PS50915"
FT   DOMAIN          88..128
FT                   /note="Beta/gamma crystallin 'Greek key'"
FT                   /evidence="ECO:0000259|PROSITE:PS50915"
FT   DOMAIN          129..171
FT                   /note="Beta/gamma crystallin 'Greek key'"
FT                   /evidence="ECO:0000259|PROSITE:PS50915"
SQ   SEQUENCE   174 AA;  20879 MW;  B01DC167171A7668 CRC64;
     MGKITFYEDR AFQGRSYETT TDCPNLQPYF SRCNSIRVES GCWMLYERPN YQGQQYLLRR
     GEYPDYQQWM GLSDSIRSCC LIPQTVSHRL RLYEREDHKG LMMELSEDCP SIQDRFHLSE
     IRSLHVLEGC WVLYELPNYR GRQYLLRPQE YRRCQDWGAM DAKAGSLRRV VDLY
//