ID A0A0V1H0H8_9BILA Unreviewed; 720 AA. AC A0A0V1H0H8; DT 16-MAR-2016, integrated into UniProtKB/TrEMBL. DT 16-MAR-2016, sequence version 1. DT 24-JAN-2024, entry version 25. DE SubName: Full=Short transient receptor potential channel 5 {ECO:0000313|EMBL:KRZ04050.1}; GN Name=TRPC7 {ECO:0000313|EMBL:KRZ04050.1}; GN ORFNames=T11_14583 {ECO:0000313|EMBL:KRZ04050.1}; OS Trichinella zimbabwensis. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia; OC Trichinellida; Trichinellidae; Trichinella. OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ04050.1, ECO:0000313|Proteomes:UP000055024}; RN [1] {ECO:0000313|EMBL:KRZ04050.1, ECO:0000313|Proteomes:UP000055024} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ04050.1}; RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.; RT "Evolution of Trichinella species and genotypes."; RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KRZ04050.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JYDP01000173; KRZ04050.1; -; Genomic_DNA. DR AlphaFoldDB; A0A0V1H0H8; -. DR STRING; 268475.A0A0V1H0H8; -. DR Proteomes; UP000055024; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro. DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR036770; Ankyrin_rpt-contain_sf. DR InterPro; IPR013555; TRP_dom. DR InterPro; IPR002153; TRPC_channel. DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1. DR PANTHER; PTHR10117:SF50; TRP HOMOLOGOUS CATION CHANNEL PROTEIN; 1. DR Pfam; PF08344; TRP_2; 1. DR SMART; SM01420; TRP_2; 1. DR SUPFAM; SSF48403; Ankyrin repeat; 1. DR PROSITE; PS50088; ANK_REPEAT; 1. PE 4: Predicted; KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}; KW Ion transport {ECO:0000256|ARBA:ARBA00023065}; KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KRZ04050.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000055024}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 329..349 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 361..381 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 401..422 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 443..465 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 485..507 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 581..605 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 630..648 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REPEAT 106..138 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT DOMAIN 141..205 FT /note="Transient receptor ion channel" FT /evidence="ECO:0000259|SMART:SM01420" SQ SEQUENCE 720 AA; 83858 MW; 0AFA5086F001A4FC CRC64; MDTKSKGDAR DIFDLIDCGK EDELANCVNK NPAVLDSENM NRFTVAQYAI LRKKWKPILK WLPKIEYRLK ETVLIAVFGS EVKVVASLLR DRRYDANSEL PVLFPDYLTP IIVAAQMGNY KMIKLLVEMG YRVPVPHRAG CICNECEMEK NHKDDVSITL LRLESYKALC NPAYLLQDIF PDPIIESFML CREMDKCIDC EPYYKDIYSG LKENLRRLPT ALILCCQTEE EAAVMLKESQ GAPVGSLTSF PRVSVAIDTD QKDFLNDPRC LTVLKKKFKG EWADWNGISN SEKVARIAVH TVGYPITSLV NVLTNGKVFK SYSTPVARFI SFATSYVIFL MCLIAFTQYK ERRDLRGAPD SLFKSIIICY VWIFLFSWFT ISWTDVIQLG FRRFLYSWWR WYDLILMSIY LLAFNAFMNS WLEVKHHGQP YAHRVHWDPY HPTLLFEVLF TFASVMASWR LFYFFQIFRA YGPIVISIGR CVKDILIFLS IFVVVVGSFA LGLNYLMEHY KGNVVLRDGK RFEQPAYMTS IESAVRYLYW AWYGYLDPER LEVVVGQFGP DKEEIKHYLV QYAAEFLSAS YYVILVVSLL NLMISIMSST AGAVLENSGK EWAYVLSQIW MEFFDDCRMI PPPFSLLQLL IHGIVYIFRR LFQRKKYKDV RLSVWNMNYK SEPQESDDKY ENLMVELKHR LLGRRALEEN FGKEAIIITE METLNIYNAI //