ID A0A0U2RXH9_9SAUR Unreviewed; 228 AA. AC A0A0U2RXH9; DT 16-MAR-2016, integrated into UniProtKB/TrEMBL. DT 16-MAR-2016, sequence version 1. DT 08-JUN-2016, entry version 4. DE RecName: Full=Cytochrome c oxidase subunit 2 {ECO:0000256|RuleBase:RU000457}; GN Name=COX2 {ECO:0000313|EMBL:ALP86020.1}; OS Lycodon flavozonatus (big-tooth snake). OG Mitochondrion {ECO:0000313|EMBL:ALP86020.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; OC Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Lycodon. OX NCBI_TaxID=1273574 {ECO:0000313|EMBL:ALP86020.1}; RN [1] {ECO:0000313|EMBL:ALP86020.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=26195217; RA Ding M., Wu J., Qian L., Pan T., Zhang B.; RT "Complete mitochondrial genome of Lycodon flavozonatum and RT implications for Colubridae taxonomy."; RL Mitochondrial DNA 1-2:0-0(2015). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. Subunit 2 CC transfers the electrons from cytochrome c via its binuclear copper CC A center to the bimetallic center of the catalytic subunit 1. CC {ECO:0000256|RuleBase:RU000457}. CC -!- COFACTOR: CC Name=Cu cation; Xref=ChEBI:CHEBI:23378; CC Evidence={ECO:0000256|RuleBase:RU000457}; CC Note=Binds a copper A center. {ECO:0000256|RuleBase:RU000457}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU000457}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU000457}. CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family. CC {ECO:0000256|RuleBase:RU000457}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KR911720; ALP86020.1; -; Genomic_DNA. DR RefSeq; YP_009193030.1; NC_028730.1. DR GeneID; 26522127; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0005507; F:copper ion binding; IEA:InterPro. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. DR GO; GO:0022900; P:electron transport chain; IEA:InterPro. DR Gene3D; 1.10.287.90; -; 1. DR Gene3D; 2.60.40.420; -; 1. DR InterPro; IPR001505; Copper_CuA. DR InterPro; IPR008972; Cupredoxin. DR InterPro; IPR002429; Cyt_c_oxidase_su2_C. DR InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom. DR Pfam; PF00116; COX2; 1. DR Pfam; PF02790; COX2_TM; 1. DR SUPFAM; SSF49503; SSF49503; 1. DR SUPFAM; SSF81464; SSF81464; 1. DR PROSITE; PS00078; COX2; 1. DR PROSITE; PS50857; COX2_CUA; 1. DR PROSITE; PS50999; COX2_TM; 1. PE 3: Inferred from homology; KW Copper {ECO:0000256|RuleBase:RU000457, ECO:0000256|SAAS:SAAS00515163}; KW Electron transport {ECO:0000256|RuleBase:RU000457, KW ECO:0000256|SAAS:SAAS00517827}; KW Membrane {ECO:0000256|RuleBase:RU000457, KW ECO:0000256|SAAS:SAAS00517788, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|RuleBase:RU000457, KW ECO:0000256|SAAS:SAAS00515158}; KW Mitochondrion {ECO:0000256|RuleBase:RU000457, KW ECO:0000313|EMBL:ALP86020.1}; KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000457}; KW Respiratory chain {ECO:0000256|RuleBase:RU000457}; KW Transmembrane {ECO:0000256|RuleBase:RU000457, KW ECO:0000256|SAAS:SAAS00470865, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00470972, KW ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|RuleBase:RU000457, KW ECO:0000256|SAAS:SAAS00517787}. FT TRANSMEM 21 44 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 64 82 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 1 92 COX2_TM. {ECO:0000259|PROSITE:PS50999}. FT DOMAIN 93 226 COX2_CUA. {ECO:0000259|PROSITE:PS50857}. SQ SEQUENCE 228 AA; 25634 MW; D5BF615E90092936 CRC64; MPHAGQLSLQ EAMGPTMEEV IFLHDHVLLL TCLMTMVITM FTLTATTTAL THNDPTEEVE QLEAAWTVAP IMILILTALP SVRSLYLMEE VFNPYLTIKA TGHQWYWNYE YSDGVKTSFD SYMIQTKDLQ NGSPRLLEVD HRMIMPAGLQ TRIVVTAEDV LHSWTIPSLG VKVDAVPGRL NQLPLATSRV GVFYGQCSEI CGANHSFMPI AMEATPLHHF EQWLISEQ //