ID A0A0U1RQ46_MOUSE Unreviewed; 609 AA. AC A0A0U1RQ46; DT 17-FEB-2016, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 1. DT 25-MAY-2022, entry version 37. DE SubName: Full=Zinc finger protein 950 {ECO:0000313|Ensembl:ENSMUSP00000146243}; GN Name=Zfp950 {ECO:0000313|Ensembl:ENSMUSP00000146243, GN ECO:0000313|MGI:MGI:2652824}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000146243, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000146243, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146243, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000146243} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146243}; RG Ensembl; RL Submitted (DEC-2015) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; NP_001296145.1; NM_001309216.1. DR AlphaFoldDB; A0A0U1RQ46; -. DR SMR; A0A0U1RQ46; -. DR DNASU; 414758; -. DR Ensembl; ENSMUST00000180544.3; ENSMUSP00000146243.2; ENSMUSG00000074733.15. DR GeneID; 414758; -. DR CTD; 414758; -. DR MGI; MGI:2652824; Zfp950. DR VEuPathDB; HostDB:ENSMUSG00000074733; -. DR GeneTree; ENSGT00940000153805; -. DR OMA; AYHSNLQ; -. DR OrthoDB; 1318335at2759; -. DR BioGRID-ORCS; 414758; 0 hits in 1 CRISPR screen. DR ChiTaRS; Zfp950; mouse. DR Proteomes; UP000000589; Chromosome 19. DR RNAct; A0A0U1RQ46; protein. DR ExpressionAtlas; A0A0U1RQ46; baseline and differential. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central. DR GO; GO:0060325; P:face morphogenesis; IMP:MGI. DR GO; GO:0030097; P:hemopoiesis; IMP:MGI. DR GO; GO:0001822; P:kidney development; IMP:MGI. DR GO; GO:0035264; P:multicellular organism growth; IMP:MGI. DR GO; GO:0006807; P:nitrogen compound metabolic process; IMP:MGI. DR GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI. DR GO; GO:0009791; P:post-embryonic development; IMP:MGI. DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central. DR GO; GO:0060021; P:roof of mouth development; IMP:MGI. DR GO; GO:0048705; P:skeletal system morphogenesis; IMP:MGI. DR GO; GO:0014909; P:smooth muscle cell migration; IMP:MGI. DR GO; GO:0048745; P:smooth muscle tissue development; IMP:MGI. DR GO; GO:0001570; P:vasculogenesis; IMP:MGI. DR CDD; cd07765; KRAB_A-box; 1. DR InterPro; IPR001909; KRAB. DR InterPro; IPR036051; KRAB_dom_sf. DR InterPro; IPR036236; Znf_C2H2_sf. DR InterPro; IPR013087; Znf_C2H2_type. DR Pfam; PF01352; KRAB; 1. DR Pfam; PF00096; zf-C2H2; 11. DR SMART; SM00349; KRAB; 1. DR SMART; SM00355; ZnF_C2H2; 18. DR SUPFAM; SSF109640; SSF109640; 1. DR SUPFAM; SSF57667; SSF57667; 10. DR PROSITE; PS50805; KRAB; 1. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 17. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 19. PE 4: Predicted; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00042}. FT DOMAIN 4..115 FT /note="KRAB" FT /evidence="ECO:0000259|PROSITE:PS50805" FT DOMAIN 75..102 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 103..130 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 131..158 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 159..186 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 187..214 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 215..242 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 243..270 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 271..298 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 299..326 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 327..354 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 355..382 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 383..410 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 411..438 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 439..466 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 467..494 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 495..522 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 523..550 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 551..578 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 579..606 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT REGION 590..609 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 609 AA; 71202 MW; 972AB8169BEEEEAF CRC64; MDAVTYDEVH VNFTQEEWAL LDHSQKSLYR DVMLETYKNL TAIGYNWDDH NIEEHCQSSR RHGRHETSHP GEKPSQYTHC GKAFVYWSHP QRHERIHTGE KPYGCNHCGK AFAHHSNLQR HERIHTGEKP YECNQCGKAF VTHSDLQIHK RTHTGEKPYE CNQCGKAFAY HSNLQRHERI HTGEKPYECN QCGKAFAYHS NLQRHERIHT GEKPYECNKC GKAFAWHSHL QRHEITHTGE KPYECNQCGK AFAHDSNLHI HKRKHAGEKP YECNQCGKAF PCYNLLQIHK RTHTGEKPYE CNQCGKTFAY HSYLQMHERI HTGEKPYECN HCGKAFSQHS SLRVHKRTHT GEKPYECNQC GEAFVYHSHL QIHKTMHTGE KPFQCNQCDK AFVYNNHLLV HKRIHTGEKP YECNHCGKAF SQLSGLHVHK RTHTGEKPYK CNECGKAFAR NSHLQRHKRI HTGEKPHECN QCGKAFARHS TLQVHKRKHA GEKPYECNQC GKAFPSHNLL HIHKRTHTGE KPYECNQCGK TFAYHSHLQV HGRIHTGEKP YKCNQCGKAF ACHRNLRVHK RKHTGEKPYE FNHYSKAFSQ HSSLQVHKRT HIGEKSYEL //