ID A0A0S3EVR3_9SPHN Unreviewed; 146 AA. AC A0A0S3EVR3; DT 17-FEB-2016, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 1. DT 17-JUN-2020, entry version 12. DE RecName: Full=Protoporphyrinogen IX oxidase {ECO:0000256|PIRNR:PIRNR004638}; DE EC=1.3.99.- {ECO:0000256|PIRNR:PIRNR004638}; GN ORFNames=ATN00_03620 {ECO:0000313|EMBL:ALR19532.1}; OS Sphingobium baderi. OC Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; OC Sphingomonadaceae; Sphingobium. OX NCBI_TaxID=1332080 {ECO:0000313|EMBL:ALR19532.1, ECO:0000313|Proteomes:UP000056968}; RN [1] {ECO:0000313|EMBL:ALR19532.1, ECO:0000313|Proteomes:UP000056968} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DE-13 {ECO:0000313|EMBL:ALR19532.1, RC ECO:0000313|Proteomes:UP000056968}; RA Cheng M., Meng Q., Yang Y., Chu C., Yan X., He J., Li S.; RT "A Two-component Flavoprotein Monooxygenase System MeaXY Responsible for RT para-Hydroxylation of 2-Methyl-6-ethylaniline and 2,6-Diethylaniline in RT Sphingobium baderi DE-13."; RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the oxidation of protoporphyrinogen IX to CC protoporphyrin IX. {ECO:0000256|PIRNR:PIRNR004638}. CC -!- CATALYTIC ACTIVITY: CC Reaction=3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX; CC Xref=Rhea:RHEA:62000, ChEBI:CHEBI:13193, ChEBI:CHEBI:17499, CC ChEBI:CHEBI:57306, ChEBI:CHEBI:57307; CC Evidence={ECO:0000256|PIRNR:PIRNR004638}; CC -!- COFACTOR: CC Name=heme b; Xref=ChEBI:CHEBI:60344; CC Evidence={ECO:0000256|PIRNR:PIRNR004638}; CC Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit. CC {ECO:0000256|PIRNR:PIRNR004638}; CC -!- PATHWAY: Porphyrin-containing compound metabolism; protoporphyrin-IX CC biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1. CC {ECO:0000256|PIRNR:PIRNR004638}. CC -!- SIMILARITY: Belongs to the HemJ family. CC {ECO:0000256|PIRNR:PIRNR004638}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP013264; ALR19532.1; -; Genomic_DNA. DR RefSeq; WP_062062262.1; NZ_CP013264.1. DR EnsemblBacteria; ALR19532; ALR19532; ATN00_03620. DR KEGG; sbd:ATN00_03620; -. DR KO; K08973; -. DR OrthoDB; 1433260at2; -. DR UniPathway; UPA00251; UER00324. DR Proteomes; UP000056968; Chromosome. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR InterPro; IPR005265; HemJ-like. DR PANTHER; PTHR40255; PTHR40255; 1. DR Pfam; PF03653; UPF0093; 1. DR PIRSF; PIRSF004638; UCP004638; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|PIRNR:PIRNR004638}; KW Heme {ECO:0000256|PIRNR:PIRNR004638}; Iron {ECO:0000256|PIRNR:PIRNR004638}; KW Membrane {ECO:0000256|PIRNR:PIRNR004638, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|PIRNR:PIRNR004638}; KW Reference proteome {ECO:0000313|Proteomes:UP000056968}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 6..28 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 56..77 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 83..104 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 125..143 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 146 AA; 16786 MW; 2F0E6BB10C2733CA CRC64; MAYLGAAYLW VKAAHLIFVI FLMAGLFMMP RFFVYHQQCA VGSDEDHKWI DRERRLLKII LNPSLLLVWI FGLMLMVEIG AWHFGWFHLK LLFVLGLSGY HGWIAGYAKK LARGERPMTD KRLRLMNEIP GVAAAVIVIA VIVKPF //