ID A0A0S2VHL5_9MYCO Unreviewed; 181 AA. AC A0A0S2VHL5; DT 17-FEB-2016, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 1. DT 16-MAR-2016, entry version 2. DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU000431}; DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU000431}; DE Flags: Fragment; GN Name=rpoB {ECO:0000313|EMBL:ALP83525.1}; OS Mycobacterium colombiense. OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; OC Mycobacterium; Mycobacterium avium complex (MAC). OX NCBI_TaxID=339268 {ECO:0000313|EMBL:ALP83525.1}; RN [1] {ECO:0000313|EMBL:ALP83525.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=10-AK {ECO:0000313|EMBL:ALP83525.1}; RA Zhang Y., Guo Z.; RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription CC of DNA into RNA using the four ribonucleoside triphosphates as CC substrates. {ECO:0000256|RuleBase:RU000432}. CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). {ECO:0000256|RuleBase:RU000431}. CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 CC beta' and 1 omega subunit. When a sigma factor is associated with CC the core the holoenzyme is formed, which can initiate CC transcription. {ECO:0000256|RuleBase:RU000433}. CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family. CC {ECO:0000256|RuleBase:RU000434}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KU198415; ALP83525.1; -; Genomic_DNA. DR Gene3D; 2.40.270.10; -; 1. DR Gene3D; 2.40.50.150; -; 1. DR InterPro; IPR015712; DNA-dir_RNA_pol_su2. DR InterPro; IPR007120; DNA-dir_RNA_pol_su2_6. DR InterPro; IPR007121; RNA_pol_bsu_CS. DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold. DR PANTHER; PTHR20856; PTHR20856; 2. DR Pfam; PF00562; RNA_pol_Rpb2_6; 1. DR PROSITE; PS01166; RNA_POL_BETA; 1. PE 3: Inferred from homology; KW DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU000431}; KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU000431}; KW Transcription {ECO:0000256|RuleBase:RU000431}; KW Transferase {ECO:0000256|RuleBase:RU000431}. FT NON_TER 1 1 {ECO:0000313|EMBL:ALP83525.1}. FT NON_TER 181 181 {ECO:0000313|EMBL:ALP83525.1}. SQ SEQUENCE 181 AA; 19818 MW; F0382E24DEBB5625 CRC64; AIFGEKAREV RDTSLKVPHG ESGKVIGIRV FSREDDDELP AGVNELVRVY VAQKRKISDG DKLAGRHGNK GVIGKILPQE DMPFLPDGTP VDIILNTHGV PRRMNIGQIL ETHLGWVAKS GWNIEGSPEW AVNLPEQLRH AQPDQIVSTP VFDGAKEEEL QGMLSCTLPN RDGEVMVNGD G //