ID A0A0S2MT38_SCAAR Unreviewed; 233 AA. AC A0A0S2MT38; DT 17-FEB-2016, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 1. DT 22-FEB-2023, entry version 18. DE SubName: Full=MHC class II antigen alpha chain {ECO:0000313|EMBL:ALO78758.1}; DE Flags: Fragment; GN Name=Scar-DXA {ECO:0000313|EMBL:ALO78758.1}; OS Scatophagus argus (Spotted scat) (Chaetodon argus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Scatophagidae; Scatophagus. OX NCBI_TaxID=75038 {ECO:0000313|EMBL:ALO78758.1}; RN [1] {ECO:0000313|EMBL:ALO78758.1} RP NUCLEOTIDE SEQUENCE. RA Wang X., Liu Z., Zhang J., Zhang T.; RT "Genomic structure, polymorphism and expression analysis of the spotted RT scat (Scatophagus argus) MHC."; RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single- CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KT176109; ALO78758.1; -; mRNA. DR AlphaFoldDB; A0A0S2MT38; -. DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW. DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW. DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW. DR Gene3D; 2.60.40.10; Immunoglobulins; 1. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003006; Ig/MHC_CS. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR011162; MHC_I/II-like_Ag-recog. DR InterPro; IPR014745; MHC_II_a/b_N. DR InterPro; IPR001003; MHC_II_a_N. DR PANTHER; PTHR19944:SF86; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN-RELATED; 1. DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF00993; MHC_II_alpha; 1. DR SMART; SM00407; IGc1; 1. DR SMART; SM00920; MHC_II_alpha; 1. DR SUPFAM; SSF48726; Immunoglobulin; 1. DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; 1. PE 2: Evidence at transcript level; KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130}; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Immunity {ECO:0000256|ARBA:ARBA00022859}; KW Membrane {ECO:0000256|SAM:Phobius}; MHC II {ECO:0000256|ARBA:ARBA00023182}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 204..227 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 100..190 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ALO78758.1" FT NON_TER 233 FT /evidence="ECO:0000313|EMBL:ALO78758.1" SQ SEQUENCE 233 AA; 25567 MW; 5AC37AABB1D5A407 CRC64; MVVLVLSCVL CVSADILHED LAIGGCSDSD GEEMYSLDGE EVWYADFINK RGVDPQPSFT DHMIYEEGTY EQAVANQQTC RQNLKVDLEA YKNPPLQLDP PSSPIVYTED DVEVGQKNVL ICHVTGFYPA PVNVSWTKNG VQVTEGTSIN VPFPNKDGSF RQTSRLEFVP QQGDMYSCTV RHRALDQPLT RIWDVEVKQP GVGPAVFCGL GLTVGLLGVA AGTFFLIKGN ECS //