ID   A0A0R7EZ18_MOUSE        Unreviewed;       287 AA.
AC   A0A0R7EZ18;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   08-MAY-2019, entry version 11.
DE   SubName: Full=MHC class II antigen beta chain {ECO:0000313|EMBL:AKN89449.1};
GN   Name=H2-Eb2 {ECO:0000313|EMBL:AKN89449.1, ECO:0000313|MGI:MGI:95902};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AKN89449.1};
RN   [1] {ECO:0000313|EMBL:AKN89449.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BALB/c {ECO:0000313|EMBL:AKN89449.1};
RA   Monzon-Casanova E., Rudolf R.;
RT   "Characterization and functional analysis of the non-polymorphic MHC
RT   class II molecules RT1-Db2 and H2-Eb2.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the MHC class II family.
CC       {ECO:0000256|SAAS:SAAS00552561}.
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DR   EMBL; KP027332; AKN89449.1; -; mRNA.
DR   MGI; MGI:95902; H2-Eb2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR   GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   Gene3D; 3.10.320.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   ProDom; PD000328; MHC_II_b_N; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   SUPFAM; SSF54452; SSF54452; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   2: Evidence at transcript level;
KW   Adaptive immunity {ECO:0000256|SAAS:SAAS00288621};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00298785};
KW   Immunity {ECO:0000256|SAAS:SAAS00288599};
KW   Membrane {ECO:0000256|SAAS:SAAS00288628, ECO:0000256|SAM:Phobius};
KW   MHC II {ECO:0000256|SAAS:SAAS00288621};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00288613,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00288610,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     29       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    227    249       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      125    213       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   287 AA;  32231 MW;  EF3489C45D295494 CRC64;
     MVSLWLPRGL CVAAVILSLM MVTPPVILVR DPRPRFLEQL KAECHYFNGK ERVWSVTRFI
     YNQEEFARFN SDFGKFLAVT ELGRPIVEYL NTQKDMLDNY RASVDRCRNN YDLVDIFMLN
     LKAEPKVTVY LAKTQPLEHH NLLVCSVIDF YPGSIEVRWF RNGEEEKTGV VSTGLIQNGD
     WTYQTLVMLG TVPRGGEVYT CQVEHLSLTS PVTVEWRTRS TSAQSKLLSG AMGMALGLFI
     LAVGLFFYLR NLRAGSVSHD AGEGAESFTS RLTGSGSECH MGPGLSI
//