ID A0A0R4J082_MOUSE Unreviewed; 520 AA. AC A0A0R4J082; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JAN-2016, sequence version 1. DT 25-MAY-2022, entry version 39. DE SubName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 1 {ECO:0000313|Ensembl:ENSMUSP00000028663}; GN Name=Creb3l1 {ECO:0000313|Ensembl:ENSMUSP00000028663, GN ECO:0000313|MGI:MGI:1347062}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000028663, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000028663, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000028663, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000028663} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000028663}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; NP_036087.2; NM_011957.2. DR SMR; A0A0R4J082; -. DR ProteomicsDB; 335105; -. DR Antibodypedia; 6395; 283 antibodies from 37 providers. DR DNASU; 26427; -. DR Ensembl; ENSMUST00000028663.5; ENSMUSP00000028663.5; ENSMUSG00000027230.10. DR GeneID; 26427; -. DR KEGG; mmu:26427; -. DR CTD; 90993; -. DR MGI; MGI:1347062; Creb3l1. DR VEuPathDB; HostDB:ENSMUSG00000027230; -. DR GeneTree; ENSGT00940000159848; -. DR OMA; TENNELW; -. DR OrthoDB; 644485at2759; -. DR PhylomeDB; A0A0R4J082; -. DR BioGRID-ORCS; 26427; 4 hits in 75 CRISPR screens. DR ChiTaRS; Creb3l1; mouse. DR Proteomes; UP000000589; Chromosome 2. DR GO; GO:0000785; C:chromatin; IEA:Ensembl. DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl. DR GO; GO:0016020; C:membrane; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IEA:Ensembl. DR GO; GO:0035497; F:cAMP response element binding; IEA:InterPro. DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl. DR GO; GO:0046332; F:SMAD binding; IEA:Ensembl. DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro. DR GO; GO:1902236; P:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; IEA:Ensembl. DR GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl. DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl. DR GO; GO:1903671; P:negative regulation of sprouting angiogenesis; IEA:Ensembl. DR GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl. DR GO; GO:1990440; P:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; IEA:Ensembl. DR InterPro; IPR004827; bZIP. DR InterPro; IPR046347; bZIP_sf. DR InterPro; IPR029805; OASIS. DR PANTHER; PTHR46004:SF1; PTHR46004:SF1; 1. DR Pfam; PF00170; bZIP_1; 1. DR SMART; SM00338; BRLZ; 1. DR SUPFAM; SSF57959; SSF57959; 1. DR PROSITE; PS50217; BZIP; 1. DR PROSITE; PS00036; BZIP_BASIC; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 290..353 FT /note="BZIP" FT /evidence="ECO:0000259|PROSITE:PS50217" FT REGION 200..259 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 450..520 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 336..356 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 207..251 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 459..490 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 520 AA; 57088 MW; DC2652AA1583A9F2 CRC64; MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFVENMEDF SNDLFSSFFD DPVLDEKSAL LDMELDSPAP GIQAEHSYSL SGDSAPQSPL VPVKMEDTTQ DVEHGAWALG NKLCSIMVKQ EQSPELPVDP LAASSAMAAA AAMATPPLLG LSPMPRLPIP HQAPGEMTQL PVIKAEPPEM SQFLKVTPED LVQMPPTPPS SHGSDSDGSQ SPRSLPPSSP VRPMARSSTA ISTSPLLTAP HKLQGTSGPL LLTEEEKRTL IAEGYPIPTK LPLTKAEEKA LKRVRRKIKN KISAQESRRK KKEYVECLEK KVETYTSENN ELWKKVETLE TANRTLLQQL QKLQTLVTSK ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPAFSSG SMTVKEDPIA ADSVYAASQM PSRSLLFYDD GAGSWEDGRG ALLPVEPPEG WELKPGGPAE QRPQDHLRHD RADSIHETTK YLRETWPEDT DDNGTSPNFS HPKEWFHDRD LGPNTTIKLS //